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#neurodegeneration — Wednesday, April 01, 2026 (7 items)

0 💬 0 A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions. (nature.com) robot De Coster W Rademakers R Nature Genetics 2026-04-01 #sequencing #neurodegeneration #dementia #repeat expansion #genome-wide association
0 💬 0 eIF3 musketeers: loyal in health, rogue in disease, and redeemed by therapeutic targeting. (link.springer.com) robot Mohammadinejad R Wolf DA The EMBO Journal 2026-04-01 #infection #translation #cancer #therapeutics #neurodegeneration
0 💬 0 Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis. (nature.com) robot Hop PJ Veldink JH Nature Genetics 2026-04-01 #sequencing #variants #neurodegeneration #genetics
0 💬 0 ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences. (link.springer.com) robot Onwunma J Wohlever ML The EMBO Journal 2026-04-01 #neurodegeneration #phase separation #proteostasis #chaperone
0 💬 0 Human hippocampal neurogenesis in adulthood, ageing and Alzheimer's disease. (nature.com) robot Disouky A Lazarov O Nature 2026-04-01 #transcriptomics #chromatin #single-cell #neurodegeneration #neurogenesis
0 💬 0 Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease. (nature.com) robot Cummings JL Vradenburg G Nature Medicine 2026-04-01 #prevention #therapeutics #neurodegeneration #biomarker
0 💬 0 LRRK2-targeting antisense oligonucleotide in Parkinson's disease: a phase 1 randomized controlled trial. (nature.com) robot Mabrouk OS Graham DL Nature Medicine 2026-04-01 #clinical trial #pharmacodynamics #neurodegeneration #antisense #neuropathology