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#amr — Wednesday, April 01, 2026 (60 items)

0 💬 0 Convergent MurJ flippase inhibition by phage lysis proteins. (nature.com) robot Li YE Clemons WM Jr Nature 2026-04-01 #cell wall #amr #protein structure #inhibition #phage
0 💬 0 Exposure-QTc modeling of bedaquiline, pretomanid, and clofazimine in adults with tuberculosis. (journals.asm.org) robot Abdelwahab MT Denti P Antimicrobial Agents and Chemotherapy 2026-04-01 #pharmacokinetics #modeling #cardiotoxicity #amr #tb
0 💬 0 Establishment of an in vivo-based assay using a silkworm infection model for phenotypic evaluation of antimicrobial drug combinations against Mycobacterium abscessus. (journals.asm.org) robot Yagi A Uchida R Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #infection #synergy #phenotypic
0 💬 0 Pharmacokinetics/pharmacodynamics of KSP-1007 in combination with meropenem against carbapenemase-producing gram-negative bacteria in a neutropenic murine thigh infection model. (journals.asm.org) robot Takemoto K Hanaki H Antimicrobial Agents and Chemotherapy 2026-04-01 #pharmacodynamics #amr #infection #pharmacokinetics #modeling
0 💬 0 Therapeutic effect of eravacycline against carbapenem-resistant hypervirulent Klebsiella pneumoniae in mouse models. (journals.asm.org) robot Zhang R Zhu M Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #virulence #infection #inflammation #colonization
0 💬 0 Model-based quantification of immune response and anti-staphylococcal activity of afabicin in immunocompetent mouse thigh infections to enable predictions of clinical efficacy. (journals.asm.org) robot Saporta R Friberg LE Antimicrobial Agents and Chemotherapy 2026-04-01 #modeling #infection #immunity #amr
0 💬 0 Iotadentification of SQ109 analogs with enhanced antimicrobial activity against methicillin-resistant Staphylococcus aureus. (journals.asm.org) robot Dellis C Mylonakis E Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #membrane #drug development
0 💬 0 Comparative genomic, phenotypic, and clinical characterization of ST11-KL25 and ST11-KL64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital, 2020-2023. (journals.asm.org) robot Li P Xiang T Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #virulence #sequencing #biofilm #infection
0 💬 0 In vitro activity of aztreonam-avibactam and distribution of carbapenemase genes in ceftazidime-avibactam-resistant carbapenem-resistant Enterobacterales: data from the global Antimicrobial Testing Leadership and Surveillance, 2019-2023. (journals.asm.org) robot Lee Y-L Hsueh P-R Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #susceptibility #surveillance
0 💬 0 Single-ascending and multiple-ascending dose study of the pharmacokinetics, safety, and tolerability of BV100 (rifabutin for infusion) in healthy volunteers. (journals.asm.org) robot Kemmer C Dale GE Antimicrobial Agents and Chemotherapy 2026-04-01 #pharmacokinetics #amr #infection #bioavailability
0 💬 0 Disarming carbapenemase-producing Acinetobacter baumannii: high potency of the novel therapeutic combination of meropenem and the innovative diazabicyclooctane beta-lactamase inhibitor pilabactam (formerly ANT3310). (journals.asm.org) robot Rodriguez-Pallares S Arca-Suarez J Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #infection
0 💬 0 A mechanism for adaptive genome regulation in cancer. (nature.com) robot Franca GS Yanai I Nature 2026-04-01 #plasticity #amr #transcription #adaptation
0 💬 0 Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation. (nature.com) robot Sastre-Dominguez J San Millan A Nature Microbiology 2026-04-01 #amr #plasmid #conjugation #transposon
0 💬 0 Clinical outcomes with oral cephalosporins as definitive treatment of Enterobacterales bacteremia from a urinary source based on cefazolin minimum inhibitory concentration. (journals.asm.org) robot Kobasuk L Nazminia K Antimicrobial Agents and Chemotherapy 2026-04-01 #bacteremia #amr #infection #colonization
0 💬 0 Functional characterization of a novel class A carbapenemase CAE-1 in carbapenem-resistant Pseudomonas aeruginosa clinical isolates. (journals.asm.org) robot Chen J Wang M Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #virulence
0 💬 0 Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition. (nature.com) robot Fiedler MK Sieber SA Nature Microbiology 2026-04-01 #proteomics #infection #amr #virulence
0 💬 0 Emergence of artemisinin-based combination therapy resistance markers in Plasmodium falciparum from the Brazilian tri-border region of the Guiana Shield. (journals.asm.org) robot Salazar YEAR de Sousa TN Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #sequencing #malaria #polymorphism #parasite
0 💬 0 Pharmacodynamic evaluation of BRII-693, a next-generation synthetic macrocyclic peptide antibiotic, in the neutropenic mouse thigh and lung infection models against gram-negative pathogens. (journals.asm.org) robot Lepak AJ Andes DR Antimicrobial Agents and Chemotherapy 2026-04-01 #pharmacodynamics #antibiotic #infection #amr #peptide
0 💬 0 Stepwise evolution and clonal enrichment of gepotidacin resistance in Neisseria gonorrhoeae. (journals.asm.org) robot Yao L Zhou P Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #gonorrhoeae #infection #phylogenomics
0 💬 0 Genome sequencing for prevention of health-care-associated bacterial infections. (nature.com) robot Hayden MK Snitkin ES Nature Reviews Microbiology 2026-04-01 #sequencing #amr #infection #plasmid #surveillance
0 💬 0 CefiderocolFinder: a tool for detecting genetic adaptations implicated in cefiderocol resistance. (linkinghub.elsevier.com) robot van den Brand B Hendrickx APA Clinical Microbiology and Infection 2026-04-01 #amr #sequencing #variant calling #bioinformatics
0 💬 0 Circulation of extended-spectrum beta-lactamase and plasmid-borne cephalosporinase-producing Escherichia coli from a One Health perspective: a narrative review. (linkinghub.elsevier.com) robot Miltgen G Armand-Lefevre L Clinical Microbiology and Infection 2026-04-01 #amr #plasmid #surveillance #zoonosis #genomics
0 💬 0 Global Analysis of the Co-Occurrence of Antimicrobial and Metal Resistance Genes in Bacterial Genomes From Dairy-Isolated Pathogens. (sfamjournals.onlinelibrary.wiley.com) robot Almeida ACO Conte-Junior CA Environmental Microbiology 2026-04-01 #amr #genomics #plasmid #metal resistance #dairy
0 💬 0 Efficacy of susceptibility-matched antibiotic treatment of nontyphoidal Salmonella bloodstream infections: a prospective observational study in hospitalized children under 5 in the Democratic of Congo. (linkinghub.elsevier.com) robot Tack B Lunguya O Clinical Microbiology and Infection 2026-04-01 #amr #infection #bacteremia #antibiotic
0 💬 0 Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals. (nature.com) robot Baldanzi G Fall T Nature Medicine 2026-04-01 #microbiome #metagenomics #amr #dysbiosis
0 💬 0 Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis. (link.springer.com) robot Dupuy P Neyrolles O The EMBO Journal 2026-04-01 #amr #metal resistance #virulence #protein assembly #tb
0 💬 0 Resistance development to new anti-Gram negatives antibiotics during treatment: geographical epidemiology and risk factors. (linkinghub.elsevier.com) robot Falcone M Shields RK Clinical Microbiology and Infection 2026-04-01 #amr #infection #epidemiology #plasmid
0 💬 0 New drugs, old problems: a narrative review of antibiotic stewardship programme in the era of novel gram-negative antibiotics. (linkinghub.elsevier.com) robot Retamar-Gentil P Carrara E Clinical Microbiology and Infection 2026-04-01 #stewardship #amr #infection #antibiotic
0 💬 0 Global survey of extraintestinal pathogenic Escherichia coli identifies stable serogroup-virulence-resistance linkages. (link.springer.com) robot Li M Wang D Genome Medicine 2026-04-01 #amr #virulence #phylogenomics #infection #pangenome
0 💬 0 Evaluation of antimicrobial resistance governance across 193 countries to inform the 2026 Global Action Plan update. (nature.com) robot Chen W Zhu Y Nature Medicine 2026-04-01 #amr #surveillance #governance #policy #one health
0 💬 0 Identification of a novel gene in Pseudomonas aeruginosa promotes persister formation by repressing translation and cell division. (journals.asm.org) robot Feng J Wu W Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #persistence #transcriptomics #translation #virulence
0 💬 0 Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study. (academic.oup.com) robot Mitri EA Trubiano JA Clinical Infectious Diseases 2026-04-01 #allergy #implementation #clinical #amr
0 💬 0 How to perform pharmacokinetic research of antimicrobial drugs in critically ill patients undergoing continuous renal replacement therapy: a scoping review of all relevant pharmacokinetic factors. (linkinghub.elsevier.com) robot Wieringa A Haringman JJ Clinical Microbiology and Infection 2026-04-01 #pharmacokinetics #dosing #renal replacement therapy #amr
0 💬 0 On the shoulders of a giant: an appraisal of the legacy of Dr. Gerald P Bodey to infectious diseases. (linkinghub.elsevier.com) robot Kontoyiannis DP Chemaly RF Clinical Microbiology and Infection 2026-04-01 #immunocompromised #infection #neutropenia #cancer #amr
0 💬 0 Homologous recombination deficiency and hemizygosity drive resistance in breast cancer. (nature.com) robot Safonov A Razavi P Nature 2026-04-01 #homologous recombination #cancer #brca2 #mutation #amr
0 💬 0 The novel second-generation triterpenoid SCY-247 maintains in vitro and in vivo activity against resistant Candida glabrata. (journals.asm.org) robot Wiederhold NP Patterson TF Antimicrobial Agents and Chemotherapy 2026-04-01 #antifungal #candidiasis #infection #amr
0 💬 0 Designing novel bisquinoline antimalarials from historical 4-aminoquinolines to combat drug-resistant malaria. (journals.asm.org) robot Handford MJ Riscoe MK Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #antimalarial #drug design #structure-activity #pharmacokinetics
0 💬 0 A Fe-incorporated bioreactor platform exhibiting antimalarial activity and enhanced response to artemisinin. (journals.asm.org) robot Li Y Lu F Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #malaria #artemisinin #nanoparticles #iron metabolism
0 💬 0 Pharmacokinetics, safety, and tolerability of HRS-8427, a novel anti-carbapenem-resistant cephalosporin, in healthy subjects. (journals.asm.org) robot Yin T Hu W Antimicrobial Agents and Chemotherapy 2026-04-01 #pharmacokinetics #amr #antibiotic #clinical trial
0 💬 0 Pseudomonas aeruginosa tRNA nucleotidyltransferase Cca controls resistance and tolerance to aminoglycoside antibiotics by regulating the MexXY multidrug efflux pump. (journals.asm.org) robot Shen C Jin Y Antimicrobial Agents and Chemotherapy 2026-04-01 #efflux #transcription #amr #aminoglycoside #tolerance
0 💬 0 Epidemiology and genomics of azithromycin-resistant extensively drug-resistant Salmonella enterica serovar Typhimurium in Taiwan. (journals.asm.org) robot Hong Y-P Chiou C-S Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #sequencing #plasmid #phylogenomics #infection
0 💬 0 Deciphering the multidrug resistance paradigm in Candida auris. (journals.asm.org) robot Santana DJ Cuomo CA Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #antifungal #infection #mutation
0 💬 0 Directed evolution of the pathogenic mold Aspergillus fumigatus reveals novel genes contributing to triazole resistance. (journals.asm.org) robot Handelman M Osherov N Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #virulence #infection #modeling
0 💬 0 Ribosomal protection as a linezolid resistance mechanism in Mycobacterium abscessus. (journals.asm.org) robot Funck T Rubin EJ Antimicrobial Agents and Chemotherapy 2026-04-01 #antibiotic #amr #ribosomal protection #mycobacteria #abc transporters
0 💬 0 Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study. (academic.oup.com) robot Mitri EA Trubiano JA Clinical Infectious Diseases 2026-04-01 #allergy #penicillin #amr #implementation
0 💬 0 PaREx: an open-source pipeline for the automated analysis of Pseudomonas aeruginosa resistomes from whole-genome sequences. (journals.asm.org) robot Lopez-Causape C Oliver A Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #sequencing #phylogenomics
0 💬 0 Molecular basis of linezolid resistance in Finegoldia spp. from orthopedic infections. (journals.asm.org) robot Jean-Pierre V Marchandin H Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #sequencing #infection #conjugation
0 💬 0 Drought drives elevated antibiotic resistance across soils. (nature.com) robot Shan X Newman DK Nature Microbiology 2026-04-01 #amr #microbiome #metagenomics #drought #selection
0 💬 0 In vivo evolution of resistance to contemporary beta-lactam/beta-lactamase inhibitor combinations during treatment of a KPC-producing Serratia marcescens infection. (journals.asm.org) robot Bailey DC Mathers AJ Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #sequencing #infection #evolution
0 💬 0 Changing genetic profiles of Plasmodium falciparum piperaquine resistance in Southeast Asia over 25 years. (journals.asm.org) robot Srisutham S Imwong M Antimicrobial Agents and Chemotherapy 2026-04-01 #amr #parasitology #malaria #polymorphism #epidemiology