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0
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IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.
(nature.com)
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Zhang X
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Su X
Nature Chemical Biology
2026-03-01
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0
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Reconstructing 3D transcriptional organization from spatial transcriptomics reveals consistent oncogenic translocations and developmental dynamics.
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Sheng Y
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Cheng Li S
Briefings in Bioinformatics
2026-03-01
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0
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Multimodal antigenic escape to GPRC5D-targeted T cell engagers in multiple myeloma.
(nature.com)
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Lee H
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Bahlis NJ
Nature Medicine
2026-03-01
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0
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Clinical-grade autonomous cytopathology through whole-slide edge tomography.
(nature.com)
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Nitta N
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Goda K
Nature
2026-03-01
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Generative design and validation of therapeutic peptides for glioblastoma based on a potential target ATP5A.
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Qian H
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Xu L
Briefings in Bioinformatics
2026-03-01
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NetCIS: a network-based common insertion site pipeline for case-control Sleeping Beauty screens.
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Fischbach MJ
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Rogers LM
Briefings in Bioinformatics
2026-03-01
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Inferring cancer type-specific patterns of metastatic spread using Metient.
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Koyyalagunta D
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Morris Q
Nature Methods
2026-03-01
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CRESCENT: a deep learning framework with multi-scale attention for detecting recurrent copy number alterations.
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Feng X
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Chen L
Briefings in Bioinformatics
2026-03-01
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A cancer-type-aware framework for robust multimodal survival prediction under missing modalities.
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Song Y
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Lin M
Briefings in Bioinformatics
2026-03-01
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Deep representation learning for temporal inference in cancer omics: a systematic literature review.
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Prol-Castelo G
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Valencia A
Briefings in Bioinformatics
2026-03-01
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Nous-209 neoantigen vaccine for cancer prevention in Lynch syndrome carriers: a phase 1b/2 trial.
(nature.com)
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D'Alise AM
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Vilar E
Nature Medicine
2026-03-01
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Enhancing cancer classification accuracy with a self-attention network using panel capture sequencing data.
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Jia Y
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Zhao Z
Briefings in Bioinformatics
2026-03-01
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#sequencing
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alpha-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers.
(nature.com)
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Mi W
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Li F
Nature Chemical Biology
2026-03-01
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Sensitive detection of copy number alterations in low-pass liquid biopsy sequencing data.
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Eriksson L
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Lakatos E
Briefings in Bioinformatics
2026-03-01
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#sequencing
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The ubiquitin ligase KLHL6 drives resistance to CD8(+) T cell dysfunction.
(nature.com)
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Cheng H
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Li G
Nature
2026-03-01
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#immunity
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ELOVL6 activity attenuation induces mutant KRAS degradation.
(nature.com)
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Hu X
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Kelley SO
Nature Chemical Biology
2026-03-01
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#kras
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0
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Activated ATF6alpha is a hepatic tumour driver restricting immunosurveillance.
(nature.com)
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Li X
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Heikenwalder M
Nature
2026-03-01
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#hepatocellular carcinoma
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0
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Microbiota-induced T cell plasticity enables immune-mediated tumour control.
(nature.com)
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Najar TA
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Littman DR
Nature
2026-03-01
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#microbiome
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0
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Treatment of acute myeloid leukemia models by targeting a cell surface RNA-binding protein.
(nature.com)
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George BM
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Tzelepis K
Nature Biotechnology
2026-03-01
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#immunotherapy
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SpaFun: discovering domain-specific spatial expression patterns and new disease-relevant genes using functional principal component analysis.
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Jiang X
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Xu L
Briefings in Bioinformatics
2026-03-01
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#transcriptomics
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0
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PDTSyn: a parameter-decomposed transformer for domain-generalized cell line-aware drug synergy prediction.
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Zeng B
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Xu L
Briefings in Bioinformatics
2026-03-01
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SigRescueR: a pan-system framework for noise correction and mutational signature identification across sequencing platforms.
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Nguyen PT
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Zhivagui M
Briefings in Bioinformatics
2026-03-01
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#mutational signatures
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Tyrosine kinase targeting uncovers oncogenic pathway plasticity in Tasmanian devil transmissible cancers.
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Schonbichler A
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Moriggl R
The EMBO Journal
2026-03-01
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#cancer
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Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry.
(nature.com)
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Li JL
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Huo D
Nature Genetics
2026-03-01
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#polygenic
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Complex-specific inhibitors for interrogating ATAC histone acetyltransferase complex.
(nature.com)
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Liu S
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Li XD
Nature Chemical Biology
2026-03-01
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#histone acetyltransferase
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DeepDrugs: a mechanism-aware tri-linear attention framework for synergistic drug-combination prediction.
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Xin G
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Liu J
Briefings in Bioinformatics
2026-03-01
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Ancestry and somatic profile indicate acral melanoma origin and prognosis.
(nature.com)
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Basurto-Lozada P
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Robles-Espinoza CD
Nature
2026-03-01
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#melanoma
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Fusobacterium nucleatum: ecology, pathogenesis and clinical implications.
(nature.com)
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Jiang SS
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Fang JY
Nature Reviews Microbiology
2026-03-01
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#pathobiont
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0
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Atlas-guided discovery of transcription factors for T cell programming.
(nature.com)
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Chung HK
…
Wang W
Nature
2026-03-01
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#transcription factor
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0
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Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC.
(nature.com)
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Sahin U
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Tureci O
Nature
2026-03-01
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#vaccination
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0
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Critical role for a high-plasticity cell state in lung cancer.
(nature.com)
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Chan JE
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Tammela T
Nature
2026-03-01
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#cancer
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Multimodal foundation models in colorectal cancer: from prediction to trustworthy clinical insight.
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Gharaie Amirabadi D
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Safarpour H
Briefings in Bioinformatics
2026-03-01
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#cancer
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Linavonkibart and pembrolizumab in immune checkpoint blockade-resistant advanced solid tumors: a phase 1 trial.
(nature.com)
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Yap TA
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Gan L
Nature Medicine
2026-03-01
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#biomarker
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0
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Proteomic analysis across Healthy-NAT-Tumor tissues uncovers clinically relevant biological events in esophageal squamous cell carcinoma.
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Liu W
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Li EM
Briefings in Bioinformatics
2026-03-01
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A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy.
(nature.com)
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Huang JL
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Yin S
Nature Chemical Biology
2026-03-01
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#autophagy
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0
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Causal modeling reveals cell-cell communication dynamics in the tumor microenvironment during anti-PD-1 therapy in breast cancer patients.
(academic.oup.com)
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Qiu A
…
Lu X
Briefings in Bioinformatics
2026-03-01
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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade.
(nature.com)
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Gonzalez-Kozlova E
…
Gnjatic S
Nature Medicine
2026-03-01
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#immunity
#immunotherapy
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0
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miRBiT: a rules-based single-sample serum miRNA classifier for pan-cancer detection with multi-cohort validation.
(academic.oup.com)
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Krishnamoorthy P
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Kumar H
Briefings in Bioinformatics
2026-03-01
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#microrna
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0
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Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types.
(nature.com)
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Everall A
…
Wedge DC
Nature Genetics
2026-03-01
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#mutation
#sequencing
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0
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Clinical development of cancer vaccines.
(nature.com)
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Haanen JB
…
Wu CJ
Nature Medicine
2026-03-01
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#clinical trial
#vaccination
#cancer
#immunotherapy
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0
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MED1 IDR deacetylation controls stress responsive genes through RNA Pol II recruitment.
(nature.com)
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Lin R
…
Roeder RG
Nature Chemical Biology
2026-03-01
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#transcription
#acetylation
#cancer
#stress
#deacetylation
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