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#cytotoxicity
— Tuesday, February 10, 2026
(2 items)
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T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B.
(pnas.org)
Johnson JE
…
Pober JS
PNAS
2026-02-10
#immunity
#transcriptomics
#inflammation
#cytotoxicity
#celiac disease
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Trogocytosis-orchestrated CLDN18.2-"dressed" CD8(+) T cells drive pancreatic cancer progression via glucose metabolic reprogramming-induced cytotoxicity debilitation and systematic immune senescence cascade.
(gut.bmj.com)
Zhou T
…
Hao J
Gut
2026-02-10
#metabolism
#cancer
#immunotherapy
#cytotoxicity
#pancreatic