|
0
|
|
Controlled dynamic remodeling of the spliceosome active site enables the first step of splicing.
(pnas.org)
|
Martino G
…
De Vivo M
PNAS
2026-01-06
|
#splicing
#spliceosome
#modeling
#catalysis
#cryo-em
|
|
0
|
|
The IGVF catalog-from genetic variation to function.
(academic.oup.com)
|
Li D
…
Wang T
Nucleic Acids Research
2026-01-06
|
#genomics
#variation
#modeling
#perturbation
|
|
0
|
|
Identifying direct risk factors in UK Biobank via simultaneous Bayesian-frequentist model-averaged hypothesis testing using Doublethink.
(pnas.org)
|
Arning N
…
Wilson DJ
PNAS
2026-01-06
|
#epidemiology
#modeling
#covid-19
#biobank
#genome-wide association
|
|
0
|
|
QSProteome: a community-driven interactive platform for large-scale exploration and evaluation of predicted protein complex structures.
(academic.oup.com)
|
Catoiu EA
…
Palsson BO
Nucleic Acids Research
2026-01-06
|
#proteomics
#modeling
#protein
|
|
0
|
|
Open Enzyme Database: a community-wide repository for sharing enzyme data.
(academic.oup.com)
|
Yuan L
…
Zhao H
Nucleic Acids Research
2026-01-06
|
#database
#enzyme
#biocatalysis
#cheminformatics
#modeling
|
|
0
|
|
RCSB Protein Data Bank: Delivering integrative structures alongside experimental structures and computed structure models.
(academic.oup.com)
|
Vallat B
…
Burley SK
Nucleic Acids Research
2026-01-06
|
#modeling
#database
#crystallography
|
|
0
|
|
Modeling and inferring metacommunity dynamics with Maximum Caliber.
(pnas.org)
|
Jackson Z
…
Xue B
PNAS
2026-01-06
|
#modeling
#metacommunity
#dynamics
#inference
|
|
0
|
|
Interpretable early warnings using machine learning in an online game-experiment.
(pnas.org)
|
Falmagne G
…
Levin SA
PNAS
2026-01-06
|
#modeling
#prediction
#machine learning
#critical-transitions
|
|
0
|
|
Artificial intelligence for improving decision-making in bacterial infection management: a narrative review.
(academic.oup.com)
|
Talianu A
…
Rawson TM
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#infection
#amr
#modeling
#diagnosis
|
|
0
|
|
SIGNOR 4.0: the 2025 update with focus on phosphorylation data.
(academic.oup.com)
|
Lo Surdo P
…
Perfetto L
Nucleic Acids Research
2026-01-06
|
#phosphorylation
#signaling
#database
#curation
#modeling
|
|
0
|
|
OmniPath: integrated knowledgebase for multi-omics analysis.
(academic.oup.com)
|
Turei D
…
Saez-Rodriguez J
Nucleic Acids Research
2026-01-06
|
#proteomics
#transcriptomics
#modeling
#metabolism
|
|
0
|
|
Towards enhanced translational value: preclinical drug activity testing against actively multiplying, nutrient-starved and pellicle biofilm-embedded Mycobacterium abscessus.
(academic.oup.com)
|
Meliefste HM
…
Bax HI
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#biofilm
#amr
#infection
#modeling
#tb
|
|
0
|
|
Antibiotic pharmacodynamics: from MIC to advanced metrics and their applications.
(academic.oup.com)
|
Andersson M
…
Aulin LBS
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacodynamics
#amr
#modeling
#infection
|
|
0
|
|
Model-based assessment of letermovir pharmacokinetics in allogeneic haematopoietic stem cell transplant recipients.
(academic.oup.com)
|
Tahtsidou C
…
Isberner N
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacokinetics
#modeling
#transplantation
#bioavailability
#drug-drug interaction
|
|
0
|
|
Development of population pharmacokinetic models of total and free piperacillin in critically ill children and young adults for Monte Carlo simulations and model-informed precision dosing.
(academic.oup.com)
|
Tang Girdwood S
…
Kaplan J
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacokinetics
#modeling
#antibiotic
#dosing
#pediatrics
|
|
0
|
|
A model-based comparison of dose reduction strategies for fixed-dose dolutegravir-containing regimens.
(academic.oup.com)
|
Dickinson L
…
Khoo S
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacokinetics
#modeling
#dosing
#hiv
|
|
0
|
|
Preclinical evaluation of epetraborole in the hollow fibre system model of Mycobacterium abscessus lung disease.
(academic.oup.com)
|
Singh S
…
Srivastava S
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#amr
#modeling
#infection
#sequencing
#tb
|
|
0
|
|
Insights from three decades of BRCA1/2 modeling in mice.
(nature.com)
|
Darnold JS
…
Jonkers J
Nature Genetics
2026-01-06
|
#modeling
#cancer
#immunity
|
|
0
|
|
Systematic review of antimicrobial pharmacokinetic/pharmacodynamic indices in murine thigh and hollow fibre dose fractionation studies analysed with a standard method.
(academic.oup.com)
|
Alabdulkarim N
…
Standing JF
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacodynamics
#pharmacokinetics
#amr
#modeling
#infection
|
|
0
|
|
MetaNetX: a bridge between metabolic resources for enhanced curation and multi-omics data harmonization.
(academic.oup.com)
|
Moretti S
…
Mehl F
Nucleic Acids Research
2026-01-06
|
#metabolism
#metabolomics
#modeling
#curation
#integration
|
|
0
|
|
MITE: the Minimum Information about a Tailoring Enzyme database for capturing specialized metabolite biosynthesis.
(academic.oup.com)
|
Rutz A
…
Zdouc MM
Nucleic Acids Research
2026-01-06
|
#metabolism
#biosynthesis
#database
#enzymes
#modeling
|
|
0
|
|
Strategies reimagined: SDG-driven solutions for combating global desertification.
(pnas.org)
|
Wang X
…
Dong Z
PNAS
2026-01-06
|
#desertification
#agriculture
#sustainability
#modeling
|
|
0
|
|
Susceptible host dynamics explain pathogen resilience to perturbations.
(pnas.org)
|
Park SW
…
Cobey S
PNAS
2026-01-06
|
#modeling
#infection
#immunity
#epidemiology
|
|
0
|
|
International Mouse Phenotyping Consortium Portal: facilitating investigation of gene function and providing insights into human disease.
(academic.oup.com)
|
Wilson R
…
Parkinson H
Nucleic Acids Research
2026-01-06
|
#phenotyping
#modeling
#knockout
#disease
|
|
0
|
|
Sticky interactions govern sequence-dependent dynamics in biomolecular condensates.
(pnas.org)
|
Muthukumar K
…
Mittal J
PNAS
2026-01-06
|
#modeling
#protein
#dynamics
#condensates
#simulation
|
|
0
|
|
GotEnzymes2: expanding coverage of enzyme kinetics and thermal properties.
(academic.oup.com)
|
Lyu B
…
Li F
Nucleic Acids Research
2026-01-06
|
#protein design
#metabolism
#enzyme kinetics
#database
#modeling
|
|
0
|
|
Deep-learning prediction of gene expression from personal genomes.
(link.springer.com)
|
Drusinsky S
…
Pollard KS
Genome Biology
2026-01-06
|
#modeling
#transcriptomics
#sequencing
#genome
|
|
0
|
|
Social networks and international migration in Honduran villages.
(pnas.org)
|
Thomas LJ
…
Garip F
PNAS
2026-01-06
|
#migration
#social networks
#modeling
|
|
0
|
|
ChromPolymerDB: a high-resolution database of single-cell 3D chromatin structures for functional genomics.
(academic.oup.com)
|
Chen M
…
Chronis C
Nucleic Acids Research
2026-01-06
|
#chromatin
#modeling
#single-cell
#genomics
#database
|
|
0
|
|
Competition for heritable wealth, not cultural group selection, drives the evolution of monogamy.
(pnas.org)
|
Saffa G
…
Duda P
PNAS
2026-01-06
|
#phylogenetic
#modeling
#evolution
#comparative
|
|
0
|
|
Reducing aztreonam/avibactam waste: insights from Monte Carlo simulations.
(academic.oup.com)
|
Fromage Y
…
Woillard JB
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacokinetics
#modeling
#amr
#dosing
|
|
0
|
|
The beta-lactamase inhibitor concentration-dependent minimum inhibitory concentration (MICcBLI) as methodology to assess the pharmacokinetic/pharmacodynamic relationship of piperacillin/tazobactam for dosing optimization.
(academic.oup.com)
|
Andersson M
…
Kloft C
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#pharmacokinetics
#pharmacodynamics
#amr
#dosing
#modeling
|
|
0
|
|
Preventing resistance development in infections by OXA beta-lactamase-producing Pseudomonas aeruginosa: correlating clinical outcomes with hollow-fibre model input.
(academic.oup.com)
|
Montero MM
…
Oliver A
Journal of Antimicrobial Chemotherapy
2026-01-06
|
#amr
#modeling
#sequencing
#infection
#pharmacodynamics
|