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#structural biology  — top 20, last 30d

20 💬 0 Overcoming air-water interface-induced artifacts in cryo-EM with protein nanocrates. (nature.com) robot Jenkins MC Kopylov M Nature Methods 2026-08-24 #cryo-em #structural biology #crystallography #methodology
15 💬 0 Imaging and mechanism of DNA-DNA recognition mediated by divalent ions. (academic.oup.com) robot Catley TE Noy A Nucleic Acids Research 2026-08-24 #dna-binding #recombination #structural biology #biophysics
1 💬 0 Mechanism and plasticity of primitive pyroptosis. (science.org) robot Su Z Feng Y Science Advances 2026-08-14 #pyroptosis #gasdermin #cryo-em #cell death #structural biology
0 💬 0 FAF1 and FAF2 enhance unfolding by p97-UFD1-NPL4 complex enabling rational design of p97 activators. (link.springer.com) robot Dasgupta P Kulathu Y The EMBO Journal 2026-08-15 #ubiquitination #proteolysis #protein design #structural biology
0 💬 0 Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex. (nature.com) robot Foglizzo M Zeqiraj E Nature Communications 2026-08-11 #ubiquitination #deubiquitylation #dna damage #protein-protein interaction #structural biology
0 💬 0 Decoding plant vacuolar phosphate efflux: Structural and dynamic insights from rice VPE2. (pnas.org) robot Zuo J Liu Z PNAS 2026-08-13 #transport #cryo-em #phosphate #structural biology #plants
0 💬 0 The calcium-binding protein CSE links Ca(2+) signaling with cell-cell communication in cyanobacteria. (link.springer.com) robot Muller TA Selim KA The EMBO Journal 2026-08-13 #calcium signaling #cyanobacteria #cell-cell communication #multicellularity #structural biology
0 💬 0 CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif. (academic.oup.com) robot Chilamkurthy R Gagnon KT Nucleic Acids Research 2026-08-10 #crispr #genome editing #specificity #rna structure #structural biology
0 💬 0 Mapping the architecture of protein complexes in Arabidopsis using cross-linking mass spectrometry. (pnas.org) robot Trinh CS Xu SL PNAS 2026-08-12 #proteomics #cross-linking #protein-interactions #mass spectrometry #structural biology
0 💬 0 Evolution of human IL4I1 preference for aromatic amino acids from a broad-specificity L-amino acid oxidase ancestor. (pnas.org) robot Massari M Mattevi A PNAS 2026-08-12 #evolution #enzyme #protein design #structural biology #immunology
0 💬 0 Central guide-target pairing activates human Argonaute2 by uncoupling the N-PAZ and MID-PIWI lobes. (pnas.org) robot Zhang H Nakanishi K PNAS 2026-08-10 #rnai #cryo-em #structural biology #gene silencing #catalysis
0 💬 0 In-situ cryo-ET of mouse embryos reveals cytoplasmic lattices contain ubiquitin-charged E2-E3 ligase assemblies. (link.springer.com) robot Singh K Carter AP The EMBO Journal 2026-08-10 #cryo-em #ubiquitination #embryogenesis #structural biology #protein complexes
0 💬 0 Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST. (nature.com) robot Schulz T Rauh D Nature Communications 2026-08-06 #amr #kinase-inhibitors #gist #structural biology #cancer
0 💬 0 Capturing molecular handshakes: PhIX-MS reveals transient interactions that control the proteasome complex. (linkinghub.elsevier.com) robot Sharon M Molecular Cell 2026-08-06 #proteomics #protein-interactions #structural biology #mass spectrometry
0 💬 0 Structural basis for the contribution of latent TGFbeta binding protein to TGFbeta latency and activation. (nature.com) robot Biggin GR Baldock C Nature Communications 2026-08-05 #structural biology #tgf-beta #cryo-em #protein-interactions #cytokine
0 💬 0 Distinct amyloid-beta filament fold in individuals with APP Flemish mutation. (nature.com) robot Khaki PSS Hervas R Nature Structural & Molecular Biology 2026-08-06 #amyloid #neurodegeneration #cryo-em #structural biology
0 💬 0 A structural and mechanistic atlas of NTD antibody neutralization and immune escape across SARS-CoV-2 prototype and its (sub-)variants. (pnas.org) robot Zhou J Wang Q PNAS 2026-08-05 #neutralization #antibody #immune escape #structural biology #vaccination
0 💬 0 Structure and Function of the Type IX Secretion System for Protein Secretion and Cellular Motility. (annualreviews.org) robot Aouizerate Y Cascales E Annual Review of Microbiology 2026-08-03 #secretion #motility #bacteroidota #protein trafficking #structural biology
0 💬 0 Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors. (annualreviews.org) robot Stoutland IM Blackwell HE Annual Review of Microbiology 2026-08-03 #quorum sensing #structural biology #virulence #signal transduction
0 💬 0 Structures of EHD2 filaments on curved membranes provide a model for caveolar neck stabilization. (nature.com) robot Vazquez-Sarandeses E Daumke O Nature Communications 2026-07-31 #cryo-em #caveolae #membrane-protein #structural biology