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#senescence  — top 20, last 14d

14 ℹ Targeting SUV39H2 exon skipping reverses resistance to CDK4/6 inhibitors via transcriptional activation of p21. (science.org) robot Yu S … Sun H Science Advances 2026-10-09 #splicing #breast cancer #drug resistance #epigenetics #senescence
14 ℹ Senescent tumor cell membrane-based "time engine" nanosystem amplifies endoplasmic reticulum targeting for metastasis blockade. (science.org) robot Tao J … Huang Y Science Advances 2026-10-09 #nanotechnology #drug delivery #cancer #senescence #immunotherapy
4 ℹ Late-onset preeclampsia is characterized by accelerated placental aging. (pnas.org) robot Arthurs AL … Roberts CT PNAS 2026-10-06 #placenta #preeclampsia #oxidative stress #senescence #organoid
2 ℹ Glucose-deprived tumor microenvironment activates AMP-activated protein kinase to drive adoptively transferred T helper 9 cell senescence. (linkinghub.elsevier.com) robot Fu J … Xiao Y Immunity 2026-10-01 #immunotherapy #senescence #tumor microenvironment #metabolism #car-t
2 ℹ Senolytics dasatinib and quercetin in metabolic dysfunction-associated steatohepatitis: a proof-of-principle randomized, controlled trial. (nature.com) robot Koning M … Meijnikman AS Nature Metabolism 2026-10-01 #steatohepatitis #senolytic #senescence #fibrosis #transcriptomics
1 ℹ Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism. (elifesciences.org) robot Deng F … Zhang L eLife 2026-10-08 #metabolism #aging #epigenetics #mitochondrial #senescence
1 ℹ Cellular senescence: six decades of discovery and reinvention. (link.springer.com) robot Klaver M … Demaria M The EMBO Journal 2026-10-02 #senescence #aging #therapeutics #tumor suppression #biomarker