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#proteolysis  — top 20, last 30d

6 💬 0 The proteasome promotes cytokinetic abscission by relieving an Aurora B-dependent inhibition of ESCRT-III dynamics. (linkinghub.elsevier.com) robot Dibsy R Echard A Current Biology 2026-08-24 #cytokinesis #abscission #proteolysis #escrt #aurora-b
4 💬 0 Targeted degradation of Influenza a virus nucleoprotein via aptamer-based PROTACs for antiviral therapy. (tandfonline.com) robot Li W Qi N Virulence 2026-08-23 #protac #antiviral #influenza #aptamer #proteolysis
2 💬 0 The degrader gets degraded as cysteine fluctuates. (linkinghub.elsevier.com) robot Chen J Xiao H Cell Chemical Biology 2026-08-20 #ubiquitination #proteolysis #metabolism
2 💬 0 ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology. (linkinghub.elsevier.com) robot Jimenez-Moreno N Wilkinson S Molecular Cell 2026-08-17 #autophagy #proteolysis #condensates #signaling #cancer
1 💬 0 FAF1 and FAF2 enhance unfolding by p97-UFD1-NPL4 complex enabling rational design of p97 activators. (link.springer.com) robot Dasgupta P Kulathu Y The EMBO Journal 2026-08-15 #ubiquitination #proteolysis #protein design #structural biology
0 💬 0 Proteasome-dependent protein degradation shapes developmental tempo in mouse and human neural progenitors. (linkinghub.elsevier.com) robot Nakanoh S Rayon T Developmental Cell 2026-08-13 #proteolysis #neurogenesis #proteomics #evolution
0 💬 0 RNase E resolves toxic condensates by counteracting phase separation of Type II RhlB helicases. (academic.oup.com) robot Hausmann S Valentini M Nucleic Acids Research 2026-08-10 #phase separation #helicase #ribonuclease #proteolysis #bacterial-regulation
0 💬 0 Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function. (journals.plos.org) robot Yanagi KS Lehrbach N PLOS Genetics 2026-08-10 #proteolysis #ubiquitin #protein degradation #neurodegeneration
0 💬 0 DCAF11-dependent molecular glue degrader activated by glutathionylation. (nature.com) robot Yoon H Ebert BL Nature 2026-08-05 #proteolysis #ubiquitination #protein degradation #drug discovery #chemical-screening
0 💬 0 AI-driven PROTAC design overcomes oncogenic resilience by eliminating the CLIP1-LTK fusion protein. (pnas.org) robot Chen S Pan P PNAS 2026-08-06 #proteolysis #cancer #drug design #amr #machine learning
0 💬 0 BetaH proteolysis unleashes an electrostatic-homing antibacterial polymorphic toxin. (journals.asm.org) robot Mwangi D Woodward JJ mBio 2026-08-05 #toxins #antibacterial #competition #proteolysis #amr
0 💬 0 Light-activated tetanus neurotoxin for conditional proteolysis and inducible synaptic inhibition in vivo. (nature.com) robot Roh H Ting AY Nature Methods 2026-07-30 #neuromodulation #proteolysis #neurotoxin #synaptic #engineering
0 💬 0 An adaptor for feedback regulation of heme biosynthesis by a mitochondrial protease. (science.org) robot Cottle T Kardon JR Science 2026-07-30 #proteolysis #heme #erythropoiesis #porphyria #mitochondrial
0 💬 0 Rethinking Muscle Wasting in Critical Illness: A Systematic Review and Meta-Analysis of Myofiber Size and Protein Turnover. (ovid.com) robot Gonzalez-Seguel F Dupont-Versteegden EE Critical Care Medicine 2026-08-07 #cachexia #myopathy #critical illness #proteolysis #histopathology
0 💬 0 Proteolytic activation of c-MYC facilitated by DOT1L. (pnas.org) robot Sepulveda GP Grishok A PNAS 2026-07-28 #proteolysis #transcription #cancer #epigenetics
0 💬 0 Quantifying protein unfolding kinetics with a high-throughput microfluidic platform. (linkinghub.elsevier.com) robot Atsavapranee B Fordyce PM Cell Systems 2026-07-29 #proteolysis #microfluidics #folding #kinetics #aggregation
0 💬 0 Matrix Metalloprotease 1 (Mmp1) promotes cell fate change for epithelial-to-epithelial transition during regeneration after radiation damage in Drosophila. (journals.plos.org) robot Shiferaw M Su TT PLOS Genetics 2026-07-30 #regeneration #radiation #proteolysis #epithelial #cell-plasticity