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#pluripotency
— top 20, last 30d
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Base editing reveals an essential role for NANOG in human embryogenesis.
(nature.com)
Bower OJ
…
Niakan KK
Nature
2026-06-25
#base-editing
#embryogenesis
#pluripotency
#genome editing
#differentiation
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A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells.
(nature.com)
Nourreddine S
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Mali P
Nature Biotechnology
2026-07-01
#crispri
#pluripotency
#single-cell
#perturbation
#transcriptomics
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Alterations in chromatin organization promote totipotent-like features in a DPPA2/DUX-dependent manner.
(link.springer.com)
Carey GI
…
Ruiz S
The EMBO Journal
2026-07-09
#reprogramming
#chromatin
#totipotency
#pluripotency
#transcriptomics
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PUMILIO proteins maintain lineage balance via post-transcriptional repression of germline fate and promotion of somatic differentiation.
(linkinghub.elsevier.com)
Lu T
…
Shi S
Cell Reports
2026-07-09
#embryogenesis
#differentiation
#post-transcriptional
#rna binding
#pluripotency
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ERK1/2 function as a central hub safeguarding primed human embryonic stem cell identity via multifaceted regulatory networks.
(linkinghub.elsevier.com)
Zhou Y
…
Jin Y
Cell Reports
2026-07-09
#pluripotency
#stem cell
#signaling
#differentiation
#transcriptomics