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4
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A multi-functional oral small molecule targeting energy and lipid metabolism to treat obesity and related metabolic disorders.
(science.org)
|
Lee JY
…
Naar AM
Science Advances
2026-08-21
|
#obesity
#lipid metabolism
#metabolic disorder
#pharmacology
#drug development
|
|
2
|
|
Hope for heart failure with preserved ejection fraction?
(science.org)
|
Blanton RM
Science Advances
2026-08-19
|
#heart failure
#signaling
#pharmacology
|
|
2
|
|
A chemigenetic endogenous Ras activity biosensor for live-cell pharmacology.
(nature.com)
|
Weeks R
…
Zhang J
Nature Chemical Biology
2026-08-19
|
#biosensor
#ras
#pharmacology
#signaling
#cancer
|
|
0
|
|
Cryo-EM structure of the bicarbonate receptor GPR30.
(elifesciences.org)
|
Kaneda S
…
Nureki O
eLife
2026-08-14
|
#cryo-em
#gpcr
#pharmacology
#homeostasis
|
|
0
|
|
Weight-loss-independent actions of GLP-1 medicines.
(linkinghub.elsevier.com)
|
Gonzalez-Rellan MJ
…
Drucker DJ
Cell Metabolism
2026-08-04
|
#pharmacology
#cardiovascular
#metabolism
#immunity
|
|
0
|
|
Pulsatile FXR activation for liver diseases.
(linkinghub.elsevier.com)
|
Sun P
…
Li W
Cell Metabolism
2026-08-04
|
#pharmacology
#hepatology
#receptor
#metabolism
|
|
0
|
|
The coordinated actions of metformin in the intestine and liver improves hyperglycemia.
(linkinghub.elsevier.com)
|
He L
…
Wondisford FE
Cell Reports
2026-08-05
|
#metabolism
#diabetes
#pharmacology
#mitochondria
#glucose
|
|
0
|
|
Activation of the angiotensin II type I receptor by a nonpeptide agonist.
(pnas.org)
|
Skiba MA
…
Kruse AC
PNAS
2026-08-04
|
#pharmacology
#receptor
#agonist
#hypertension
#crystallography
|
|
0
|
|
NT-A9, a new triazole, exhibits potent antifungal activity against Candida and Cryptococcus species through potent ergosterol biosynthesis inhibition.
(journals.asm.org)
|
Zhu S
…
Lu H
Antimicrobial Agents and Chemotherapy
2026-08-05
|
#antifungal
#azole
#amr
#infection
#pharmacology
|
|
0
|
|
Efficacy and safety of once-weekly subcutaneous zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.
(linkinghub.elsevier.com)
|
Mora P
…
Rosenstock J
The Lancet
2026-07-30
|
#diabetes
#pharmacology
#clinical trial
#therapeutics
|
|
0
|
|
Efficacy and safety of once-daily oral zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in adults with type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.
(linkinghub.elsevier.com)
|
Mora P
…
Rosenstock J
The Lancet
2026-07-30
|
#diabetes
#pharmacology
#clinical trial
#therapeutics
|
|
0
|
|
Effects of liraglutide on gut bacterial community dynamics.
(journals.asm.org)
|
Bull J
…
Mirza BS
Microbiology Spectrum
2026-08-03
|
#microbiome
#sequencing
#obesity
#pharmacology
|
|
0
|
|
Nicotine E-Cigarettes for Cigarette Smoking Cessation: Recommendations to US-Based Clinicians.
(jamanetwork.com)
|
Leavens ELS
…
Johnson AL
JAMA
2026-07-30
|
#smoking
#cessation
#nicotine
#pharmacology
#clinical
|
|
0
|
|
TRPM8 is a non-canonical target of 7-nitrobenzodiazepines.
(linkinghub.elsevier.com)
|
Elkin L
…
Marchant JS
Cell Chemical Biology
2026-07-29
|
#pharmacology
#ion channel
#benzodiazepines
#agonist
#neuropathy
|
|
0
|
|
Thiazolidinedione Use and Risk of Bacterial Enteric Infection Among Adults With Type 2 Diabetes Mellitus.
(academic.oup.com)
|
Birabaharan M
…
Zarrinpar A
Open Forum Infectious Diseases
2026-08-01
|
#infection
#diabetes
#pharmacology
#microbiome
#colonization
|
|
0
|
|
Diagnosis and management of acute hyperkalaemia.
(bmj.com)
|
Rech MA
…
Howington GT
BMJ
2026-08-21
|
#hyperkalemia
#electrolyte
#arrhythmia
#nephrology
#pharmacology
|