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0
|
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Development and validation of a rabbit model of Pseudomonas aeruginosa hyperdynamic septic shock for preclinical drug development.
(journals.asm.org)
|
Tran ND
…
Diep BA
Antimicrobial Agents and Chemotherapy
2026-06-15
|
#sepsis
#modeling
#infection
#amr
#pharmacokinetics
|
|
0
|
|
Plasma and intrapulmonary pharmacokinetics of funobactam, a novel diazabicyclooctane beta-lactamase inhibitor, administered in combination with imipenem/cilastatin in healthy subjects.
(journals.asm.org)
|
Rodvold K
…
Li J
Antimicrobial Agents and Chemotherapy
2026-06-15
|
#pharmacokinetics
#amr
#infection
|
|
0
|
|
Anopheles mosquitoes exposed to long-acting antimalarials via drug-supplemented bloodmeal absorb drug but do not suffer fitness costs.
(academic.oup.com)
|
Goheen MM
…
Parikh S
Journal of Infectious Diseases
2026-06-15
|
#antimalarial
#vector
#pharmacokinetics
#toxicology
|
|
0
|
|
Population pharmacokinetics of vancomycin in serum and cerebrospinal fluid: variability in cerebrospinal fluid concentrations despite targeted serum exposure.
(journals.asm.org)
|
Polaskova L
…
Sima M
Antimicrobial Agents and Chemotherapy
2026-06-15
|
#pharmacokinetics
#modeling
#meningitis
#drug penetration
#cns infection
|
|
0
|
|
Phase I dose-ascending, safety, and pharmacokinetics study of APC148, a novel metallo-beta-lactamase inhibitor, in healthy volunteers.
(journals.asm.org)
|
Bolstad B
…
Rongved P
Antimicrobial Agents and Chemotherapy
2026-06-17
|
#pharmacokinetics
#amr
#clinical trial
#infection
|
|
0
|
|
Discovery and characterization of a hydroxypyridone-3-carboxamide analog as an antiviral lead against orthopoxviruses.
(journals.asm.org)
|
Pant A
…
Yang Z
Antimicrobial Agents and Chemotherapy
2026-06-18
|
#antiviral
#drug discovery
#orthopoxviruses
#screening
#pharmacokinetics
|
|
0
|
|
Challenging Weight-Tiered Antibiotic Prophylaxis in Obese Patients Undergoing Colorectal Surgery Using CT-Derived Body Composition.
(academic.oup.com)
|
Pai MP
…
Wang S
Clinical Infectious Diseases
2026-06-20
|
#pharmacokinetics
#prophylaxis
#obesity
#dosing
#surgery
|
|
0
|
|
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite.
(journals.asm.org)
|
Xu Y
…
Lad L
Antimicrobial Agents and Chemotherapy
2026-06-22
|
#pharmacokinetics
#metabolism
#antiviral
#enzymology
#covid-19
|
|
0
|
|
Three fluoroquinolones with different epithelial lining fluid penetration in a murine lung infection model: an experimental site-specific PK/PD study.
(journals.asm.org)
|
Hosoi A
…
Matsumoto K
Antimicrobial Agents and Chemotherapy
2026-06-22
|
#pharmacokinetics
#pneumonia
#fluoroquinolones
#pharmacodynamics
#amr
|
|
0
|
|
Population pharmacokinetics of dalbavancin: external validation, model averaging, and implications for precision dosing in prolonged therapy.
(journals.asm.org)
|
Sayadi H
…
Woillard J-B
Antimicrobial Agents and Chemotherapy
2026-06-22
|
#pharmacokinetics
#dosing
#infection
#modeling
#validation
|
|
0
|
|
Safety, pharmacokinetics, and exploratory efficacy of the oral ghrelin receptor agonist AC01 in heart failure with reduced ejection fraction (GOAL-HF1): a randomised, double-blind, placebo-controlled, phase 1b/2a study.
(linkinghub.elsevier.com)
|
Lund LH
…
Petrie MC
The Lancet
2026-06-24
|
#inotrope
#heart failure
#pharmacokinetics
#clinical trial
#cardiology
|
|
0
|
|
Isavuconazole as primary antifungal prophylaxis in pediatric hematological patients: a clinical and pharmacokinetic analysis.
(journals.asm.org)
|
Baccelli F
…
Masetti R
Antimicrobial Agents and Chemotherapy
2026-06-26
|
#prophylaxis
#pediatric
#antifungal
#pharmacokinetics
#immunosuppression
|
|
0
|
|
Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing.
(academic.oup.com)
|
Petit PR
…
Solas C
Journal of Antimicrobial Chemotherapy
2026-07-02
|
#pharmacokinetics
#antiviral
#drug-distribution
#pharmacodynamics
#repurposing
|
|
0
|
|
Incidence and factors associated with subtherapeutic cefazolin levels among patients with severe infections.
(academic.oup.com)
|
Shah S
…
Smith BJ
Journal of Antimicrobial Chemotherapy
2026-07-02
|
#pharmacokinetics
#endocarditis
#antibiotic
#infection
#sepsis
|
|
0
|
|
Breaking down barriers to improve phage therapy delivery.
(linkinghub.elsevier.com)
|
Luong T
…
Bollyky PL
Cell Host & Microbe
2026-07-08
|
#phage-therapy
#drug delivery
#amr
#pharmacokinetics
#formulation
|
|
0
|
|
Predictive accuracy of population meropenem models in critically ill pneumonia patients.
(journals.asm.org)
|
Valadez A
…
Rhodes NJ
Antimicrobial Agents and Chemotherapy
2026-07-10
|
#pharmacokinetics
#pneumonia
#critically-ill
#bayesian
#renal replacement therapy
|
|
0
|
|
Central nervous system antituberculosis drug exposures in a rabbit model of tuberculous meningitis.
(journals.asm.org)
|
Calderin JM
…
Gengenbacher M
Antimicrobial Agents and Chemotherapy
2026-07-10
|
#tb
#pharmacokinetics
#meningitis
#cns
#bioavailability
|
|
0
|
|
Safety evaluation of pretomanid, an anti-tuberculosis drug, for the treatment of pregnant and lactating women.
(journals.asm.org)
|
Bruning-Barry R
…
Beumont M
Antimicrobial Agents and Chemotherapy
2026-07-10
|
#tb
#pregnancy
#toxicology
#amr
#pharmacokinetics
|