|
0
|
|
Mechanistic modeling of recessive disease through allelic integration of variant effects.
(linkinghub.elsevier.com)
|
Cubuk H
…
Kudla G
Cell Systems
2026-06-17
|
#modeling
#mutagenesis
#pathogenicity
#metabolism
|
|
0
|
|
Persistence of large mtDNA rearrangements linked to premature aging in Pol gamma exonuclease-deficient mice.
(academic.oup.com)
|
Wu S
…
Copeland WC
Nucleic Acids Research
2026-06-22
|
#mitochondrial
#aging
#sequencing
#mutagenesis
#dna repair
|
|
0
|
|
A cannabidiol-sensitive region involved in the allosteric modulation of the alpha7 nicotinic receptor.
(pnas.org)
|
Chrestia JF
…
Bouzat C
PNAS
2026-06-23
|
#simulation
#allosteric
#cannabidiol
#nicotinic receptor
#mutagenesis
|
|
0
|
|
The mutational landscape of STING-induced immunity.
(nature.com)
|
Zhang B
…
Ablasser A
Nature
2026-06-24
|
#mutagenesis
#immunity
#signaling
#interferon
|
|
0
|
|
Deciphering protein mutation-phenotype linkages from CRISPR-based tiling mutagenesis screens.
(linkinghub.elsevier.com)
|
He W
…
Xu H
Cell Systems
2026-06-26
|
#crispr
#mutagenesis
#proteomics
#phenotyping
#pathogenicity
|
|
0
|
|
Dual functional genomics reveals a broad and convergent landscape of asciminib resistance in BCR::ABL1.
(link.springer.com)
|
Sokirniy I
…
Pritchard J
Genome Medicine
2026-06-27
|
#mutagenesis
#amr
#leukemia
#kinase
#epistasis
|
|
0
|
|
Mutational scanning reveals substrate-assisted autoregulation of the WNT destruction complex.
(nature.com)
|
Padmanarayana M
…
Rohatgi R
Nature Genetics
2026-07-02
|
#mutagenesis
#wnt signaling
#colorectal cancer
#protein-protein interaction
#beta-catenin
|
|
0
|
|
Genetic dissection of DNA damage tolerance in Bacillus subtilis: RecA and recombination functions regulate translesion synthesis.
(academic.oup.com)
|
Torres R
…
Alonso JC
Nucleic Acids Research
2026-07-03
|
#translesion synthesis
#dna repair
#mutagenesis
#recombination
#bacterial genetics
|
|
0
|
|
EMS mutation and SNP detection in intracellular Wolbachia genomes.
(journals.asm.org)
|
Penunuri G
…
Russell SL
mSystems
2026-07-06
|
#mutagenesis
#sequencing
#snp
#endosymbiont
#wolbachia
|
|
0
|
|
Optimised genome editing for precise DNA insertion and substitution using prime editors in zebrafish.
(elifesciences.org)
|
Ono Y
…
Scholpp S
eLife
2026-07-07
|
#genome editing
#crispr
#prime-editing
#mutagenesis
|
|
0
|
|
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing.
(nature.com)
|
Price D
…
Radzisheuskaya A
Nature Genetics
2026-07-08
|
#histone
#crispr
#chromatin
#epigenetics
#mutagenesis
|
|
0
|
|
Highly frequent undesired insertional mutagenesis during Drosophila genome editing.
(journals.plos.org)
|
Kallstig E
…
McCabe BD
PLOS Genetics
2026-07-09
|
#crispr
#genome editing
#mutagenesis
#hdr
|
|
0
|
|
Mind the gap: An embedding guide to safely travel in sequence space.
(journals.plos.org)
|
Wu A
…
Angioletti-Uberti S
PLOS Computational Biology
2026-07-09
|
#protein design
#mutagenesis
#enzyme design
#machine learning
#computational biology
|
|
0
|
|
Engineered ADARs enable precision A-to-G base editing of DNA.
(nature.com)
|
Im HW
…
Bae S
Nature Biotechnology
2026-07-10
|
#base-editing
#crispr
#gene therapy
#mutagenesis
|
|
0
|
|
High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution.
(nature.com)
|
Wasserman HI
…
Gordan R
Nature Communications
2026-07-10
|
#transcription
#dna damage
#mutagenesis
#uv
#cancer
|