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15
|
|
The UVA-induced single-base mutational signature of CX-5461 in human cells.
(academic.oup.com)
|
Zaikova E
…
Aparicio S
Nucleic Acids Research
2026-08-24
|
#mutagenesis
#sequencing
#photochemistry
#toxicology
|
|
13
|
|
RhoA wild-type allele loss unleashes the cancer driver function of RhoA E40Q.
(jci.org)
|
Noujarede J
…
Brakebusch C
Journal of Clinical Investigation
2026-08-25
|
#carcinogenesis
#oncogenes
#squamous-cell-carcinoma
#genome instability
#mutagenesis
|
|
11
|
|
Barcoded mutant library enables high-throughput functional genomics in a filamentous fungus.
(pnas.org)
|
Huberman LB
…
Glass NL
PNAS
2026-08-25
|
#mutagenesis
#fungal
#functional genomics
#sequencing
#transformation
|
|
7
|
|
Determinants of mutation susceptibility along the genome are largely invariant across human tissues.
(link.springer.com)
|
Schmalohr CL
…
Beyer A
Genome Biology
2026-08-22
|
#mutagenesis
#somatic_mutations
#chromatin
#computational modeling
#cancer evolution
|
|
1
|
|
Characterization of genetically effective cells and EMS mutagenesis on the novel winter oil seed Pennycress (Thlaspi arvense).
(academic.oup.com)
|
Brusa A
…
Marks D
G3: Genes, Genomes, Genetics
2026-08-22
|
#mutagenesis
#sequencing
#reverse genetics
#crop-improvement
|
|
1
|
|
Redesign of energetically frustrated regions rescues function in defective T4 clamp loaders.
(academic.oup.com)
|
Nimkar S
…
Kuriyan J
Molecular Biology and Evolution
2026-08-17
|
#protein design
#mutagenesis
#atpase
#phage
#dna replication
|
|
0
|
|
Mutant p53 reactivation and DNA demethylation in the treatment of AML/MDS.
(science.org)
|
Song H
…
Lu M
Science Translational Medicine
2026-08-12
|
#leukemia
#p53
#methylation
#immunotherapy
#mutagenesis
|
|
0
|
|
Reassessing the role of progesterone receptor isoforms PGR-A and PGR-B in female fertility.
(science.org)
|
Dinh DT
…
Russell DL
Science Advances
2026-08-12
|
#fertility
#reproduction
#progesterone
#mutagenesis
|
|
0
|
|
A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli.
(academic.oup.com)
|
Fan X
…
Liu R
Nucleic Acids Research
2026-08-10
|
#base-editing
#mutagenesis
#metabolic-engineering
#screening
#genome editing
|
|
0
|
|
Systematic mapping of insertion-tolerant regions enables capsid engineering of an infectious RNA phage.
(journals.asm.org)
|
Choi S-Y
…
Cho Y-H
mBio
2026-08-10
|
#phage
#mutagenesis
#protein design
#virion
#reverse genetics
|
|
0
|
|
Identification of genes promoting fitness of a plant-associated Salmonella Choleraesuis strain on alfalfa sprouts during cold storage.
(journals.asm.org)
|
Beck M
…
Esteban-Cuesta I
Applied and Environmental Microbiology
2026-08-10
|
#transposon
#foodborne
#persistence
#mutagenesis
|
|
0
|
|
Polymerase iota promotes C>T substitutions in smoking models and in the platinum chemotherapy-induced SBS31 mutation signature.
(pnas.org)
|
Engel B
…
Nemeth E
PNAS
2026-08-06
|
#translesion synthesis
#mutagenesis
#dna damage
#chemotherapy
#mutation-signatures
|
|
0
|
|
The S32 amino acid deletion in the GP5 protein modulates the infectivity of porcine reproductive and respiratory syndrome virus.
(tandfonline.com)
|
Zhou X
…
Wang X
Virulence
2026-08-06
|
#virology
#mutagenesis
#pathogenicity
#immunology
#vaccination
|
|
0
|
|
The shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations.
(nature.com)
|
Aube S
…
Landry CR
Nature Ecology & Evolution
2026-08-03
|
#adaptation
#fitness
#mutagenesis
#regulation
#yeast
|
|
0
|
|
X-chromosome inactivation draws L1 mutagenesis to the human X chromosome.
(science.org)
|
de Los Rios Barreda J
…
Faulkner GJ
Science
2026-07-30
|
#retrotransposon
#x-inactivation
#mutagenesis
#sequencing
#genomic instability
|
|
0
|
|
A targeted mutational strategy aiding in generating antisense RNA to knockdown the Ehrlichia chaffeensis P28-outer membrane protein 19 expression.
(journals.asm.org)
|
Tong X
…
Ganta RR
Journal of Bacteriology
2026-08-04
|
#mutagenesis
#antisense
#knockdown
#ehrlichia
#pathogen
|
|
0
|
|
A NHEJ1 mutator allele influencing germline mutation rates sex-specifically in humans.
(science.org)
|
Wu K
…
Liu H
Science Advances
2026-07-31
|
#mutagenesis
#genome-wide association
#germline
#dna repair
#polymorphism
|
|
0
|
|
Markerless gene deletion in Porphyromonas gingivalis using a pheS*-based counterselection system.
(journals.asm.org)
|
Kim H-M
…
Yu M
Microbiology Spectrum
2026-08-04
|
#mutagenesis
#genetic engineering
#periodontitis
#counterselection
|
|
0
|
|
D347G in PA is critical for the pathogenicity of H9N2 avian influenza A virus in mice.
(tandfonline.com)
|
Zhao Z
…
Wan Z
Virulence
2026-08-02
|
#influenza
#virulence
#zoonosis
#mutagenesis
|
|
0
|
|
Analysis of cancer mutations introduced into the Drosophila melanogaster Notch negative regulatory region uncovers a diversity of regulatory outcomes.
(elifesciences.org)
|
Shimizu H
…
Baron M
eLife
2026-08-04
|
#oncogene
#signaling
#leukemia
#mutagenesis
|