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#lysosomal  — top 20, last 30d

3 ℹ Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates. (pnas.org) robot Wu X … Yan N PNAS 2026-10-06 #cholesterol #lysosomal #transport #structural #niemann-pick
1 ℹ A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation. (nature.com) robot Esposito A … Napolitano G Nature 2026-09-30 #autophagy #lysosomal #signaling #lymphoma #proteostasis
0 ℹ The Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis. (nature.com) robot Sheokand PK … Petkevicius K Nature Cell Biology 2026-09-15 #lipid metabolism #lysosomal #neurodegeneration #enzyme-catalysis #storage-disorder
0 ℹ Lipids regulate export of lysosomal enzymes from the endoplasmic reticulum. (pnas.org) robot Xia B … Perrimon N PNAS 2026-09-17 #lipid #lysosomal #trafficking #metabolism