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#ion channel  — top 20, last 30d

16 ℹ A bifunctional actuator to correct loss-of-function deficits in cardiac voltage-gated sodium channels. (science.org) robot Fossier L … Ben-Johny M Science Advances 2026-10-09 #ion channel #channelopathy #arrhythmia #cardiac #protein design
11 ℹ Transient receptor potential channel activation targets multiple stages of the schistosome parasite. (science.org) robot Kulkarni S … Spangenberg T Science Translational Medicine 2026-10-07 #schistosomiasis #parasite #anthelmintic #amr #ion channel
9 ℹ A histidine-mediated supramolecular mechanism links temperature and pH activation of the sperm channel CatSper. (journals.plos.org) robot Zhao B … Lishko PV PLOS Biology 2026-10-09 #ion channel #fertility #electrophysiology #structural-modeling #comparative genomics
8 ℹ Mechanisms of intracellular pH gating and local anesthetic inhibition of the two-pore domain K(+) channel TASK-2. (pnas.org) robot Docter T … Brohawn SG PNAS 2026-10-08 #ion channel #electrophysiology #cryo-em #gating #pharmacology
6 ℹ Diversity and spatial segregation of TRP channels in the closest relatives of animals. (pnas.org) robot Mannsaker S … Colgren J PNAS 2026-10-07 #evolution #sensory #ion channel #comparative genomics #choanoflagellates
1 ℹ Neuronal and non-neuronal TRPA1 mediate distinct pain perception mechanisms in Familial Episodic Pain Syndrome models. (jci.org) robot Marini M … De Logu F Journal of Clinical Investigation 2026-10-01 #nociception #pain #ion channel #allodynia #mechanotransduction
1 ℹ PKD2-like proteins target Chlamydomonas PKD2 to distinct subciliary regions. (pnas.org) robot Das P … Lechtreck K PNAS 2026-09-29 #cilia #chlamydomonas #genome editing #protein localization #ion channel
1 ℹ Distribution and voltage dependence of ion channels shape single-neuron computations. (pnas.org) robot Vieira RM … Groschner LN PNAS 2026-09-29 #ion channel #electrophysiology #neuronal #neuroscience #computational modeling
1 ℹ The Ca(2+) channel CYCLIC NUCLEOTIDE GATED CHANNEL13 regulates vasculature-mediated systemic Ca(2+) and jasmonate signaling on herbivory. (pnas.org) robot Kumari M … Vadassery J PNAS 2026-09-29 #calcium signaling #herbivory #defense #ion channel
0 ℹ Forward genetics reveals a conserved CNBHD-CNBHD interface that restrains EAG channel activation to regulate sleep. (journals.plos.org) robot Huang X … Wang H PLOS Genetics 2026-10-01 #ion channel #electrophysiology #sleep #forward-genetics #neurophysiology
0 ℹ Ligand-induced activation of RyR1 in native membranes. (nature.com) robot Mikirtumov V … Kudryashev M Nature Communications 2026-09-24 #cryo-em #calcium #ion channel #muscle #membrane-structure
0 ℹ MCA1 mechanosensitive channels enable fast communication of wound signals between lateral roots. (science.org) robot Baudon A … Hedrich R Science Advances 2026-09-25 #mechanosensing #signaling #ion channel #wound-response
0 ℹ Biophysically inspired mean-field model of neuronal populations driven by ion-exchange mechanisms. (elifesciences.org) robot Rabuffo G … Jirsa V eLife 2026-09-30 #neuron #modeling #ion channel #brain
0 ℹ PKD2L1 channels segregated to the apical compartment are the dual-mode pH sensor in cerebrospinal fluid-contacting neurons. (elifesciences.org) robot Vitar M … Trigo FF eLife 2026-09-29 #ion channel #electrophysiology #ph-sensing #mechanotransduction #neurosensory
0 ℹ Voltage-sensor conformational microenvironments encode isoform-selective ion channel activation. (pnas.org) robot Manville RW … Abbott GW PNAS 2026-09-23 #ion channel #electrophysiology #simulation #neurophysiology #drug binding
0 ℹ Structures of the volume-regulated anion channel LRRC8A/D in activating and inhibiting conditions. (nature.com) robot Lehmann EF … Dutzler R Nature Communications 2026-09-17 #ion channel #membrane proteins #cryo-em #electrophysiology #structural biology
0 ℹ Molecular mechanism of calcium inhibition in viral channelrhodopsins. (nature.com) robot Zabelskii D … Gordeliy V Nature Communications 2026-09-16 #ion channel #neuromodulation #calcium signaling #crystallography
0 ℹ TRPM2 is a direct pain transducer. (pnas.org) robot Varghese L … Zhang X PNAS 2026-09-16 #nociception #pain #ion channel #neuroinflammation #arthritis
0 ℹ Hemiplegic migraine: genetics and pathophysiology. (jci.org) robot Pietrobon D Journal of Clinical Investigation 2026-09-15 #migraine #genetics #neurophysiology #ion channel #animal-models
0 ℹ Monte Carlo modeling of the formation and organization of ion channel clustering. (journals.plos.org) robot Moise N … Weinberg SH PLOS Computational Biology 2026-09-17 #modeling #ion channel #clustering #membrane organization #computational biology