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5
|
|
Structural origins of species-specific differences in TRPV2 activation.
(nature.com)
|
Fricke TC
…
Moiseenkova-Bell VY
Nature Communications
2026-08-20
|
#electrophysiology
#ion channel
#cryo-em
#structure-function
|
|
5
|
|
Atomic structure and plasticity of the CTX-MthK complex investigated by cryo-EM, NMR, and MD simulations.
(nature.com)
|
Qoraj D
…
Lange A
Nature Communications
2026-08-20
|
#cryo-em
#toxins
#ion channel
#nmr
#simulation
|
|
2
|
|
Structural basis of ligand recognition and gating in a heteromeric Deg-3/Des-2 nicotinic acetylcholine receptor.
(pnas.org)
|
Ning Y
…
Ge J
PNAS
2026-08-20
|
#cryo-em
#nicotinic-receptors
#ion channel
#anthelmintic
|
|
1
|
|
An ER retention motif controls the heteromeric stoichiometry of hERG1a/1b channels.
(pnas.org)
|
Kannan S
…
Robertson GA
PNAS
2026-08-18
|
#ion channel
#stoichiometry
#protein assembly
#long-qt-syndrome
#trafficking
|
|
1
|
|
Sub-millivolt voltage imaging reveals gap junction-mediated bioelectric contact inhibition.
(nature.com)
|
Ruhl P
…
Heinemann SH
Nature Communications
2026-08-15
|
#bioelectric
#gap-junctions
#voltage-imaging
#ion channel
#multicellular
|
|
0
|
|
Orally available Colivin traps TRPV3 in an inactive state and suppresses intestinal inflammation.
(link.springer.com)
|
Wang Y
…
Cao Z
The EMBO Journal
2026-08-13
|
#trpv3
#colitis
#inflammation
#ion channel
#drug design
|
|
0
|
|
A TREK that activates thermogenic adipose tissue by sensing cold air in the lung.
(linkinghub.elsevier.com)
|
Tu ADJ
…
Simcox JA
Developmental Cell
2026-08-12
|
#thermogenesis
#adipose
#ion channel
#mechanosensing
|
|
0
|
|
Allosteric switching of Ca(2+) permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.
(link.springer.com)
|
Mu Q
…
Patel S
The EMBO Journal
2026-08-07
|
#ion channel
#calcium signaling
#allosteric-regulation
#biased agonism
#lysosomes
|
|
0
|
|
Identification of novel functional sites in the Ca(v)1.3 calcium channel alpha1-subunit using evolutionary modeling.
(pnas.org)
|
Tang X
…
Liedl KR
PNAS
2026-08-03
|
#ion channel
#computational biology
#variant prediction
#electrophysiology
#neurodevelopmental-disorders
|
|
0
|
|
Batrachotoxin-sensitive sodium channels in toxic birds challenge "target mutation" strategy of toxin autoresistance.
(linkinghub.elsevier.com)
|
Gromilina E
…
Abderemane-Ali F
iScience
2026-08-04
|
#toxicology
#electrophysiology
#ion channel
#evolution
#amr
|
|
0
|
|
Transient receptor potential vanilloid 2 functions as a directional driver for hepoxilin A(3)-mediated neutrophil migration.
(science.org)
|
Feriotti C
…
Mrsny R
Science Advances
2026-07-31
|
#neutrophil
#chemotaxis
#ion channel
#cell migration
#inflammation
|
|
0
|
|
TRPM8 is a non-canonical target of 7-nitrobenzodiazepines.
(linkinghub.elsevier.com)
|
Elkin L
…
Marchant JS
Cell Chemical Biology
2026-07-29
|
#pharmacology
#ion channel
#benzodiazepines
#agonist
#neuropathy
|
|
0
|
|
Protection against Babesia infection by red blood cell PIEZO1 activation.
(journals.asm.org)
|
Wengelnik K
…
Douguet D
Microbiology Spectrum
2026-07-29
|
#parasitology
#infection
#drug discovery
#ion channel
|