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#homologous recombination  — top 20, last 30d

7 ℹ A genome-scale adaptation map identifies the FANCM-RMI1/2 complex as an opposing modulator of cell fitness upon BRCA1 or BRCA2 loss. (linkinghub.elsevier.com) robot Dossin F … Deriano L Molecular Cell 2026-10-06 #cancer #homologous recombination #genomic instability #synthetic lethality #parp-inhibitors
1 ℹ Expanding the therapeutic scope of PARP inhibitors in breast cancer: current indications and future directions. (jci.org) robot Walmsley CS … Lynce F Journal of Clinical Investigation 2026-10-01 #breast cancer #parp-inhibitors #homologous recombination #synthetic lethality #biomarker
1 ℹ Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment. (nature.com) robot Baeten JT … Bolton KL Nature Genetics 2026-09-28 #hematopoiesis #homologous recombination #clonal evolution #chemotherapy #neoplasms
0 ℹ PUM3 is an essential suppressor of replication stress in homologous recombination deficient breast cancer. (nature.com) robot Amodeo V … Tutt ANJ Nature Communications 2026-09-21 #homologous recombination #replication stress #breast cancer #dna repair #synthetic lethality
0 ℹ ISWI/CHRAC orchestrates sequential chromatin-remodeling activities by mobilizing DNA polymerase epsilon for homologous recombination. (nature.com) robot Qian J … Ui A Communications Biology 2026-09-15 #chromatin #dna repair #homologous recombination #genome stability
0 ℹ Loss of Ku70 promotes mononucleate conidiation and homologous recombination in Phanerochaete chrysosporium. (journals.asm.org) robot Wu H … Liu K Applied and Environmental Microbiology 2026-09-14 #genome editing #homologous recombination #dna repair #lignin-degradation #fungal-genetics