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10
|
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Genome editing for hereditary angioedema: A landmark trial and important unanswered questions.
(linkinghub.elsevier.com)
|
Cancian M
…
Margaglione M
Cell Med
2026-10-09
|
#crispr
#gene therapy
#angioedema
#genome editing
#clinical trial
|
|
5
|
|
Discovery and engineering of avian R2 retrotransposons for all-RNA-mediated targeted DNA integration in human cells.
(nature.com)
|
Chen Y
…
Li W
Nature Biotechnology
2026-10-05
|
#retrotransposon
#genome editing
#integration
#engineering
|
|
2
|
|
Editing cells in place: Targeted in vivo gene editing of hematopoietic stem cells.
(linkinghub.elsevier.com)
|
Luozhong S
…
Li B
Cell Stem Cell
2026-10-01
|
#genome editing
#hematopoietic
#stem-cells
#gene therapy
#nanoparticles
|
|
2
|
|
Flipping the fetal switch across beta-hemoglobinopathies.
(linkinghub.elsevier.com)
|
Harwani N
…
Sharma A
Cell Stem Cell
2026-10-01
|
#genome editing
#hemoglobinopathy
#thalassemia
#base-editing
#sickle-cell
|
|
2
|
|
Reactivation of the embryonic zeta-globin gene ameliorates severe forms of alpha-thalassemia.
(nature.com)
|
Liu S
…
Higgs DR
Nature Genetics
2026-10-01
|
#genome editing
#thalassemia
#hemoglobinopathy
#erythroid
#transcriptional-regulation
|
|
2
|
|
Transposon end recognition and pairing by I-F3 CRISPR-associated transposase.
(science.org)
|
Truong VH
…
Kellogg EH
Science Advances
2026-10-02
|
#crispr
#transposition
#transposase
#cryo-em
#genome editing
|
|
2
|
|
Toward transgenic multicellular parasites: CRISPR-Cas12a germline editing of Schistosoma mansoni eggs as key to success.
(science.org)
|
Moescheid MF
…
Grevelding CG
Science Advances
2026-10-02
|
#crispr
#transgenesis
#genome editing
#schistosomiasis
#parasite
|
|
1
|
|
Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency.
(science.org)
|
Wolff JH
…
Mikkelsen JG
Science Translational Medicine
2026-09-30
|
#genome editing
#base-editing
#immunodeficiency
#hematopoietic
#stem-cells
|
|
1
|
|
Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing.
(nature.com)
|
Dong S
…
Li B
Nature Biotechnology
2026-09-28
|
#nanoparticles
#genome editing
#rna-delivery
#lipid
#base-editing
|
|
1
|
|
PKD2-like proteins target Chlamydomonas PKD2 to distinct subciliary regions.
(pnas.org)
|
Das P
…
Lechtreck K
PNAS
2026-09-29
|
#cilia
#chlamydomonas
#genome editing
#protein localization
#ion channel
|
|
0
|
|
Pyridoxine supplementation amelioratesSGPL1 R222Q variant sphingosine phosphate lyase insufficiency syndrome in mice.
(doi.org)
|
Khan R
…
Saba JD
Journal of Clinical Investigation
2026-09-24
|
#sphingolipids
#nephropathy
#enzyme-deficiency
#genome editing
#supplementation
|
|
0
|
|
Size and sequence variation of the Lid of the Cas12a nuclease domain results in a nickase phenotype.
(academic.oup.com)
|
Villegas Warren R
…
van der Oost J
Nucleic Acids Research
2026-09-22
|
#crispr
#nickase
#cryo-em
#genome editing
#protein design
|
|
0
|
|
Targeted genomic integration and rearrangement using prime assembly.
(nature.com)
|
Levesque S
…
Bauer DE
Nature
2026-09-16
|
#crispr
#genome editing
#integration
#therapeutic
|
|
0
|
|
Accurate characterization of CRISPR-Cas9 genome editing outcomes and mosaicism with near-perfect long reads.
(link.springer.com)
|
Hoijer I
…
Ameur A
Genome Medicine
2026-09-15
|
#crispr
#genome editing
#sequencing
#mosaicism
#off-target
|
|
0
|
|
Screening for dual sgRNAs with comparable indel efficiencies enhances CRISPR-mediated large-fragment deletion.
(academic.oup.com)
|
Zu Y
…
Chen L
Genetics
2026-09-16
|
#crispr
#genome editing
#deletion
#mutagenesis
|
|
0
|
|
Loss of Ku70 promotes mononucleate conidiation and homologous recombination in Phanerochaete chrysosporium.
(journals.asm.org)
|
Wu H
…
Liu K
Applied and Environmental Microbiology
2026-09-14
|
#genome editing
#homologous recombination
#dna repair
#lignin-degradation
#fungal-genetics
|