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#differentiation  — top 20, last 30d

0 💬 0 A human induced pluripotent stem cell model for the holistic study of epithelial-to-mesenchymal transitions. (nature.com) robot Hookway C Rafelski SM Nature Methods 2026-06-15 #emt #differentiation #imaging #morphogenesis #stem cell
0 💬 0 RNF126 is a peroxisomal fate switch enabling redifferentiation therapy in hepatocellular carcinoma. (pnas.org) robot Su Q Zhang Y PNAS 2026-06-16 #hepatocellular carcinoma #hypoxia #autophagy #metabolism #differentiation
0 💬 0 Development of a robust method to derive human trophoblast stem cells from late-gestation placentas and its application to preeclampsia. (pnas.org) robot Oike A Okae H PNAS 2026-06-16 #preeclampsia #placenta #differentiation #invasion #stem cell
0 💬 0 Derivation of elephant induced pluripotent stem cells. (nature.com) robot Appleton E Hysolli E Nature Methods 2026-06-22 #reprogramming #differentiation #transcriptomics #conservation #stem cell
0 💬 0 Dynamics and master transcription factors dependence of intestinal super-enhancers during differentiation and oncogenesis. (academic.oup.com) robot Fang W Chen L Nucleic Acids Research 2026-06-22 #enhancer #differentiation #transcriptomics #colorectal cancer #intestinal epithelium
0 💬 0 MAPK/ERK signaling regulates H3K9me3 heterochromatin reorganization to confer mesendoderm developmental competence. (academic.oup.com) robot Matsui S Iwafuchi M Nucleic Acids Research 2026-06-22 #epigenetics #differentiation #chromatin #signaling #stem cell
0 💬 0 ZEB1 drives terminal erythroid maturation by controlling the GATA2-KLF1 regulatory switch. (academic.oup.com) robot Kinoo A Soler E Nucleic Acids Research 2026-06-22 #erythropoiesis #transcription #differentiation #hematopoiesis
0 💬 0 Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation. (nature.com) robot Nomura M Suva ML Nature Genetics 2026-06-22 #methylation #glioma #transcriptomics #differentiation #single-cell
0 💬 0 Elevated MyoD1 levels expand genome-wide binding and the repertoire of regulated genes. (pnas.org) robot Whitney ON Tjian R PNAS 2026-06-23 #transcriptomics #transcription #chromatin #differentiation #myogenesis
0 💬 0 Reconstituting human primitive streak formation through extra-embryonic cell coordination. (linkinghub.elsevier.com) robot Shen Q Wei Y Cell 2026-06-24 #gastrulation #embryogenesis #differentiation #stem-cells #developmental biology
0 💬 0 Epiblast diversification and blood formation in a human pregastrula. (nature.com) robot Xiao Z Lan Y Nature 2026-06-24 #transcriptomics #hematopoiesis #embryogenesis #differentiation
0 💬 0 Srr2-dependent SOX2 levels govern the chromatin and transcriptional landscape of adult neural stem cell fate decisions in mouse. (link.springer.com) robot Cruces-Salguero S Moncho-Amor V Genome Biology 2026-06-25 #neurogenesis #chromatin #stem-cells #transcriptomics #differentiation
0 💬 0 Base editing reveals an essential role for NANOG in human embryogenesis. (nature.com) robot Bower OJ Niakan KK Nature 2026-06-25 #base-editing #embryogenesis #pluripotency #genome editing #differentiation
0 💬 0 Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis. (elifesciences.org) robot Zhao C Wei J eLife 2026-06-29 #spermatogenesis #differentiation #crispr #signaling #androgen
0 💬 0 Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation. (elifesciences.org) robot Lee CZW Ginhoux F eLife 2026-06-29 #hepatotoxicity #ipsc #immunology #differentiation #coculture
0 💬 0 A unified analysis of cell type- and trajectory-associated pathways in single-cell data using Phoenix. (genome.cshlp.org) robot Halperin Y Rabani M Genome Research 2026-06-29 #transcriptomics #pathway analysis #single-cell #differentiation
0 💬 0 Coordination of N(2)-fixing cell specialization and patterning in filamentous cyanobacteria by a uniquely structured sigma factor. (pnas.org) robot Hu X Xu X PNAS 2026-07-01 #differentiation #cyanobacteria #transcriptomics #patterning #regulation
0 💬 0 Opposing function of AEBP2 isoforms fine-tune PRC2 catalytic activity. (academic.oup.com) robot Li Y Lee CH Nucleic Acids Research 2026-07-03 #epigenetics #histone #chromatin #differentiation
0 💬 0 Time-resolved morphological and transcriptomic characterization of early enteric neuron subtype emergence in chick. (pnas.org) robot Andre M Falk J PNAS 2026-07-06 #transcriptomics #differentiation #neurogenesis #axonogenesis #embryogenesis
0 💬 0 Electron tomography reveals mitochondrial network and cristae remodelling during cell differentiation in the human placenta. (nature.com) robot Acharya S Fisher JJ Nature Communications 2026-07-08 #mitochondria #electron tomography #differentiation #proteomics #morphology