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8
|
|
Carbonic anhydrase VIII regulates IP3R1-dependent Ca(2+) signaling to coordinate insulin secretion and hepatic glucose production.
(science.org)
|
Fauzi M
…
Yabe D
Science Advances
2026-10-09
|
#calcium
#diabetes
#signaling
#insulin
#metabolism
|
|
6
|
|
Oral small-molecule GLP-1RA safiglipron versus dapagliflozin in type 2 diabetes: a randomized, double-blind, active-comparator-controlled phase 3 trial.
(nature.com)
|
Guo L
…
Ye Z
Nature Medicine
2026-10-05
|
#diabetes
#clinical trial
#pharmacotherapy
#glycemic control
|
|
3
|
|
Short-term risk prediction model for pancreatic cancer in type 2 diabetes: development and validation across two independent Chinese cohorts.
(doi.org)
|
Zhu H
…
Hao J
Gut
2026-10-06
|
#cancer
#diabetes
#prediction
#screening
#validation
|
|
2
|
|
Spatial and single-nucleus transcriptomics reveals the molecular pathology of type 2 diabetes-associated cognitive dysfunction.
(pnas.org)
|
Wu W
…
Ma N
PNAS
2026-10-06
|
#transcriptomics
#diabetes
#cognition
#neurodegeneration
#neuron
|
|
2
|
|
Effects of semaglutide on kidney disease in type 2 diabetes: a randomized placebo-controlled trial.
(nature.com)
|
Tuttle KR
…
Kretzler M
Nature Medicine
2026-10-01
|
#transcriptomics
#diabetes
#nephrology
#fibrosis
#endothelial
|
|
2
|
|
Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes.
(nejm.org)
|
Wharton S
…
Kaplan LM
New England Journal of Medicine
2026-10-01
|
#clinical trial
#diabetes
#obesity
#pharmacotherapy
#metabolism
|
|
1
|
|
Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.
(linkinghub.elsevier.com)
|
Klein KR
…
Meskimen ER
The Lancet
2026-09-30
|
#diabetes
#cardiovascular
#safety
#glp-1
#pharmacotherapy
|
|
1
|
|
Akkermansia muciniphila protects diabetes-associated cognitive decline by enhancing leucine catabolism and suppressing neuronal excessive mitophagy.
(tandfonline.com)
|
Ye X
…
Zheng H
Gut Microbes
2026-09-30
|
#microbiome
#diabetes
#cognition
#mitophagy
#metabolism
|
|
0
|
|
Hepatic FoxO1 loss leads to pancreatic beta cell deficiency via liver-derived C18/22/24 ceramides.
(linkinghub.elsevier.com)
|
Gong Y
…
Han D
Cell Chemical Biology
2026-10-01
|
#lipidomics
#ceramides
#diabetes
#apoptosis
#signaling
|
|
0
|
|
A high-throughput assay for the measurement of Ca(2+) oscillations and insulin release from uniformly sized mouse beta-cell (MIN6) spheroids.
(elifesciences.org)
|
Robben S
…
Voets T
eLife
2026-10-05
|
#insulin
#spheroids
#screening
#calcium
#diabetes
|
|
0
|
|
Decomposing population differences in type 2 diabetes through a high-resolution GWAS of ~600,000 individuals with East Asian ancestry.
(nature.com)
|
Saito K
…
Terao C
Communications Biology
2026-09-30
|
#diabetes
#genome-wide association
#ancestry
#polygenic
#metabolism
|