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#cryo-em  — top 20, last 30d

0 💬 0 Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15. (pnas.org) robot Liang X Muller U PNAS 2026-06-16 #cryo-em #mechanotransduction #protein structure #hearing
0 💬 0 Structure of the pre-initiation complex explains CMGE biogenesis. (nature.com) robot Puhringer T Costa A Nature 2026-06-17 #replication #cryo-em #protein structure #helicase
0 💬 0 Structure-based design of Sec61 translocon targeting prodrugs minimize off-target toxicity. (linkinghub.elsevier.com) robot Hao Q Yao G Cell Chemical Biology 2026-06-18 #cryo-em #structure_based_design #prodrug #cancer #protein-drug interaction
0 💬 0 Structure and substrate recognition by the bacterial twin-arginine translocation (Tat) core complex. (nature.com) robot Deme JC Lea SM Nature Microbiology 2026-06-22 #protein transport #cryo-em #membrane proteins #virulence
0 💬 0 Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation. (academic.oup.com) robot Guyet A Murray H Nucleic Acids Research 2026-06-22 #replication #helicase #protein-interactions #cryo-em
0 💬 0 Structural insights into RNA recognition by the Staphylococcus aureus exoribonuclease YhaM. (pnas.org) robot Mattingly JM Dunham CM PNAS 2026-06-23 #exoribonuclease #virulence #cryo-em #rna binding #protein structure
0 💬 0 Structural basis for lysophosphatidic acid recognition and atypical Galpha(q) coupling by LPAR5. (pnas.org) robot Li X Zhao LH PNAS 2026-06-23 #gpcr #cryo-em #signaling
0 💬 0 Pyrodictium abyssi AbpX reveals a calcium-responsive family of microbial biomatrix proteins that form thermostable hydrogels. (pnas.org) robot Sleutel M Conticello VP PNAS 2026-06-23 #biofilm #protein assembly #extremophile #biomatrix #cryo-em
0 💬 0 EasyGrid: a versatile platform for automated cryo-EM sample preparation and quality control. (nature.com) robot Gemin O Papp G Nature Methods 2026-06-23 #cryo-em #sample-preparation #structural biology #vitrification #automation
0 💬 0 Structure of Human adenovirus 7 virus-like particles, a platform for developing nanotherapeutics and studying capsid assembly. (pnas.org) robot Madoo K Khayat R PNAS 2026-06-23 #vaccination #immunogenicity #cryo-em #assembly #virion
0 💬 0 Structural insights into the recruitment of viral type 2 IRES to ribosomal preinitiation complex for protein synthesis. (elifesciences.org) robot Das D Hussain T eLife 2026-06-25 #translation #ires #picornavirus #cryo-em #ribosome
0 💬 0 Illuminating the molecular basis of human daylight vision. (science.org) robot Schmidt SL Isaikina P Science 2026-06-25 #photoreception #cryo-em #vision #gpcrs #spectroscopy
0 💬 0 Cryo-electron microscopy structures of human cone visual pigments. (science.org) robot Peng Q Zhang J Science 2026-06-25 #cryo-em #opsins #vision
0 💬 0 Structural insights into spectral tuning and retinal exchange in cone visual pigments. (science.org) robot Ohashi S Kandori H Science 2026-06-25 #spectroscopy #vision #cryo-em #protein structure #photoreception
0 💬 0 Conformational changes of the baseplate regulating tail contraction of Staphylococcus phage 812. (link.springer.com) robot Binovsky J Plevka P The EMBO Journal 2026-06-26 #phage #cryo-em #contractile-tails #structural biology #infection-mechanism
0 💬 0 Cryo-EM of the eukaryotic purine transporter UapA demonstrates intramolecular and lipid regulation of transport. (pnas.org) robot Broutzakis G Gatsogiannis C PNAS 2026-06-26 #cryo-em #transporter #structural biology #purine #antifungal
0 💬 0 Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC. (link.springer.com) robot Busch M Kedrov A The EMBO Journal 2026-06-26 #membrane proteins #protein-translocation #cryo-em #folding #insertase
0 💬 0 Thick filament molecular interfaces play a critical role in the pathogenesis of hypertrophic cardiomyopathy. (pnas.org) robot Dutta D Padron R PNAS 2026-06-29 #cardiomyopathy #structural biology #protein-interactions #variants #cryo-em
0 💬 0 Dynamic positioning of Rpc34 winged helix in RNA polymerase III elongation complex for its stability with implications for reinitiation. (pnas.org) robot Wu JS Chang WH PNAS 2026-06-29 #transcription #rna polymerase #cryo-em #smfret #protein dynamics
0 💬 0 Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles. (nature.com) robot Maddipatla A Bronstein AM Nature Biotechnology 2026-06-29 #structure prediction #nmr #cryo-em #protein dynamics #ensemble-methods