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10
|
|
Cryo-EM structures of Cdr1 reveal snapshots of substrate transport and diverse inhibitor recognition.
(science.org)
|
Wang Z
…
Yu X
Science Advances
2026-08-28
|
#cryo-em
#antifungal
#multidrug-resistance
#transporters
#drug design
|
|
9
|
|
Structural and mechanistic insights into gating and allosteric modulation of GluN1-GluN3A NMDA receptors.
(nature.com)
|
Kim J
…
Gouaux E
Nature Structural & Molecular Biology
2026-08-28
|
#receptor
#neurophysiology
#cryo-em
#allosteric
#neurotransmission
|
|
9
|
|
Universal pipeline for high-resolution GPCR structure determination.
(nature.com)
|
Kojima A
…
Kato HE
Nature Structural & Molecular Biology
2026-08-28
|
#cryo-em
#gpcr
#drug discovery
|
|
8
|
|
Primate-specific regulation of the human glycosphingolipid gatekeeper UGCG.
(nature.com)
|
Wu C
…
Xu HE
Nature
2026-08-26
|
#glycosphingolipids
#cryo-em
#enzyme
#membrane
#catalysis
|
|
7
|
|
Structural insights into fosfomycin efflux by a streptococcal ABC transporter.
(pnas.org)
|
Taguchi A
…
Nishino K
PNAS
2026-08-28
|
#amr
#cryo-em
#transporter
|
|
6
|
|
Structural insights into the outer membrane proteins PorA, OMP50 and Cj0034c from native Campylobacter jejuni membranes.
(journals.plos.org)
|
Zhang Z
…
Yu EW
PLOS Biology
2026-08-28
|
#cryo-em
#outer-membrane-proteins
#campylobacter
#host-pathogen
|
|
6
|
|
Insulin-like growth factor-binding protein 7 is a soluble cell adhesion molecule.
(science.org)
|
Cai K
…
Bai XC
Science Advances
2026-08-26
|
#cryo-em
#cell adhesion
#protein structure
#signaling
|
|
6
|
|
The structure of the native cardiac crossbridge in the rigor state.
(science.org)
|
Risi CM
…
Galkin VE
Science Advances
2026-08-26
|
#myosin
#structural biology
#cryo-em
#contractility
|
|
6
|
|
Structural and functional analysis of LarC, a CTP-dependent cyclometallase required for nickel-pincer nucleotide cofactor biosynthesis.
(science.org)
|
Wolfe R
…
Kim KH
Science Advances
2026-08-26
|
#metalloproteins
#cofactor-biosynthesis
#cryo-em
#catalysis
#enzyme mechanism
|
|
5
|
|
Overcoming air-water interface-induced artifacts in cryo-EM with protein nanocrates.
(nature.com)
|
Jenkins MC
…
Kopylov M
Nature Methods
2026-08-24
|
#cryo-em
#structural biology
#crystallography
#methodology
|
|
4
|
|
Topogenic sequence recognition at TIM complexes revealed by a stendomycin-bound structure.
(nature.com)
|
Chen Y
…
Park E
Nature Chemical Biology
2026-08-26
|
#cryo-em
#mitochondria
#protein-translocation
#structural biology
#membrane proteins
|
|
3
|
|
Multidomain interaction governs the filamentous assembly of the dominant-negative DNMT3A R882H mutant.
(pnas.org)
|
Chen J
…
Song J
PNAS
2026-08-25
|
#cryo-em
#protein structure
#methyltransferase
#epigenetics
#leukemia
|
|
3
|
|
A bundled anti-parallel cytochrome nanowire structure suggests roles in cell-cell electron transfer and biofilm formation.
(journals.asm.org)
|
Petersen HA
…
Wang F
mBio
2026-08-26
|
#biofilm
#cytochrome
#electron transfer
#cryo-em
#extracellular
|
|
2
|
|
Structural basis of GSDME pore formation and its regulation by S-palmitoylation.
(pnas.org)
|
Du G
…
Wu H
PNAS
2026-08-24
|
#pyroptosis
#cryo-em
#gasdermin
#palmitoylation
#immunity
|
|
1
|
|
Structural origins of species-specific differences in TRPV2 activation.
(nature.com)
|
Fricke TC
…
Moiseenkova-Bell VY
Nature Communications
2026-08-20
|
#electrophysiology
#ion channel
#cryo-em
#structure-function
|
|
1
|
|
Atomic structure and plasticity of the CTX-MthK complex investigated by cryo-EM, NMR, and MD simulations.
(nature.com)
|
Qoraj D
…
Lange A
Nature Communications
2026-08-20
|
#cryo-em
#toxins
#ion channel
#nmr
#simulation
|
|
1
|
|
A biased allosteric modulator is a molecular glue for beta(2)AR dimerization.
(nature.com)
|
Shen J
…
Kobilka BK
Nature
2026-08-19
|
#allosteric
#dimerization
#gpcr
#cryo-em
#signaling
|
|
1
|
|
Structural basis for target discrimination and activation by Cas13d.
(science.org)
|
Chou CW
…
Finkelstein IJ
Science Advances
2026-08-19
|
#crispr
#cryo-em
#antisense rna
#specificity
#nuclease
|
|
1
|
|
Structural basis of ligand recognition and gating in a heteromeric Deg-3/Des-2 nicotinic acetylcholine receptor.
(pnas.org)
|
Ning Y
…
Ge J
PNAS
2026-08-20
|
#cryo-em
#nicotinic-receptors
#ion channel
#anthelmintic
|
|
0
|
|
Quinone-transporting filaments expand bioenergetic capacity in Gram-positive Bacillota.
(nature.com)
|
Kropp A
…
Grinter R
Nature Microbiology
2026-08-17
|
#bioenergetics
#respiration
#cryo-em
#membrane
#protein complexes
|