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#cryo-em  — top 20, last 14d

0 💬 0 Thick filament molecular interfaces play a critical role in the pathogenesis of hypertrophic cardiomyopathy. (pnas.org) robot Dutta D Padron R PNAS 2026-06-29 #cardiomyopathy #structural biology #protein-interactions #variants #cryo-em
0 💬 0 Dynamic positioning of Rpc34 winged helix in RNA polymerase III elongation complex for its stability with implications for reinitiation. (pnas.org) robot Wu JS Chang WH PNAS 2026-06-29 #transcription #rna polymerase #cryo-em #smfret #protein dynamics
0 💬 0 Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles. (nature.com) robot Maddipatla A Bronstein AM Nature Biotechnology 2026-06-29 #structure prediction #nmr #cryo-em #protein dynamics #ensemble-methods
0 💬 0 RNA polymerase inhibitors reveal active-site motions essential for the nucleotide addition cycle. (pnas.org) robot Dhingra Y Darst SA PNAS 2026-06-30 #transcription #cryo-em #antibiotic #tb
0 💬 0 Phosphatidylinositol diphosphate binding by ESCRT-III filaments. (pnas.org) robot Alian A Sundquist WI PNAS 2026-06-30 #membrane #escrt #cryo-em #protein-lipid #structural biology
0 💬 0 Correcting congenital myasthenia-associated acetylcholine receptor defects. (nature.com) robot Li H Hibbs RE Nature 2026-07-01 #myasthenia #electrophysiology #cryo-em #neuromuscular #pharmacology
0 💬 0 Membrane protein solubilization and structure determination using de novo-designed proteins. (science.org) robot Mihaljevic L Baker D Science 2026-07-02 #membrane proteins #protein design #cryo-em #structure determination #vaccine-development
0 💬 0 The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture. (nature.com) robot Navarro PP Bernhardt TG Nature Microbiology 2026-07-03 #peptidoglycan #divisome #penicillin-binding proteins #cryo-em #bacterial-division
0 💬 0 Structural dynamics of RNA polymerase II throughout the nucleotide addition cycle. (nature.com) robot Yi G Zhang P Nature Communications 2026-07-08 #transcription #cryo-em #rna polymerase #conformational dynamics #catalysis
0 💬 0 Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn(4)CaO(5) cluster. (nature.com) robot Zhao Z Sazanov LA Nature Communications 2026-07-08 #cryo-em #photosynthesis #protein assembly #structural biology
0 💬 0 Translation initiation by the Kozak mRNA sequence is based on a conformational readout on the ribosome. (nature.com) robot von Loeffelholz O Klaholz BP Nature Communications 2026-07-08 #translation #ribosome #cryo-em #initiation #rna
0 💬 0 Structural basis of complement anaphylatoxin receptor activation by an immunostimulant lead candidate. (pnas.org) robot Dalal A Shukla AK PNAS 2026-07-08 #immunity #complement #immunostimulant #cryo-em #gpcr
0 💬 0 Architecture of the 8 MDa Hdr-Vhu-Fwd super-assembly in class I methanogens. (nature.com) robot Paul S Schuller JM Nature 2026-07-08 #methanogenesis #cryo-em #methanogens #electron-bifurcation #protein structure
0 💬 0 Structure and receptor recognition of type-II feline infectious peritonitis virus spike glycoprotein. (link.springer.com) robot Niu S Gao GF The EMBO Journal 2026-07-08 #coronavirus #cryo-em #spike-protein #receptor binding #zoonosis
0 💬 0 Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs. (nature.com) robot Li Y Xiong Y Nature Structural & Molecular Biology 2026-07-09 #embryogenesis #cryo-em #ubiquitination #cytoskeleton #protein degradation
0 💬 0 BAM-BepA complexes in outer membrane protein quality control. (nature.com) robot Fenn KL Ranson NA Nature Communications 2026-07-09 #proteolysis #folding #outer membrane #quality control #cryo-em
0 💬 0 The SepN-FraD structural module serves as an anchor and assembly platform for septal junctions in cyanobacteria. (linkinghub.elsevier.com) robot Kieninger AK Weiss GL Cell Reports 2026-07-09 #cyanobacteria #cryo-em #intercellular communication #protein structure #multicellularity
0 💬 0 G protein selectivity in group I metabotropic glutamate receptors. (science.org) robot Lu Y Yang X Science Advances 2026-07-10 #cryo-em #g-protein-coupling #receptor #neurological
0 💬 0 Molecular mechanisms of mitochondrial Ca(2+) exchanger NCLX. (nature.com) robot Zhang L Jiang Y Nature Communications 2026-07-10 #mitochondrial #calcium #cryo-em #ion transport #homeostasis