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#checkpoint
— top 20, last 30d
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13
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B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma.
(jci.org)
Dhodapkar KM
…
Dhodapkar MV
Journal of Clinical Investigation
2026-08-25
#immunotherapy
#melanoma
#autoimmunity
#checkpoint
#toxicity
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0
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Fc-optimized GITR antibody enhances a CD4 T cell-dendritic cell crosstalk to promote antitumor immunity.
(nature.com)
Avraham Y
…
Dahan R
Nature Cancer
2026-08-05
#antibody
#immunotherapy
#immunity
#cancer
#checkpoint
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0
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RTF2 and CLASPIN localize CHK1 to the replication fork to control S-phase progression.
(science.org)
Broton C
…
Smogorzewska A
Science Advances
2026-08-05
#replication
#checkpoint
#dna damage
#kinase
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0
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Intratumoural plasma cells mediate a pro-inflammatory response to kinase inhibition and successful immune checkpoint blockade therapy in malignant peripheral nerve sheath tumours.
(linkinghub.elsevier.com)
Lingo JJ
…
Quelle DE
EBioMedicine
2026-08-01
#immunotherapy
#sarcoma
#transcriptomics
#checkpoint
#kinase-inhibitors
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0
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Macropinocytosis of neutrophil extracellular trap by gastric cancer cells promotes immune escape and peritoneal metastasis.
(gut.bmj.com)
Chen Q
…
Zhuo W
Gut
2026-07-28
#immunity
#metastasis
#gastric cancer
#neutrophil
#checkpoint
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0
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PD-L1 restrains T-cell immunity in Nile tilapia by suppressing activation-induced fatty acid synthesis.
(academic.oup.com)
Zhang J
…
Wei X
Journal of Immunology
2026-08-04
#immunity
#t cell
#metabolism
#immunosuppression
#checkpoint