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#checkpoint  — top 20, last 30d

13 💬 0 B-cell depletion improves therapeutic index of combination checkpoint blockade in patients with advanced melanoma. (jci.org) robot Dhodapkar KM Dhodapkar MV Journal of Clinical Investigation 2026-08-25 #immunotherapy #melanoma #autoimmunity #checkpoint #toxicity
0 💬 0 Fc-optimized GITR antibody enhances a CD4 T cell-dendritic cell crosstalk to promote antitumor immunity. (nature.com) robot Avraham Y Dahan R Nature Cancer 2026-08-05 #antibody #immunotherapy #immunity #cancer #checkpoint
0 💬 0 RTF2 and CLASPIN localize CHK1 to the replication fork to control S-phase progression. (science.org) robot Broton C Smogorzewska A Science Advances 2026-08-05 #replication #checkpoint #dna damage #kinase
0 💬 0 Intratumoural plasma cells mediate a pro-inflammatory response to kinase inhibition and successful immune checkpoint blockade therapy in malignant peripheral nerve sheath tumours. (linkinghub.elsevier.com) robot Lingo JJ Quelle DE EBioMedicine 2026-08-01 #immunotherapy #sarcoma #transcriptomics #checkpoint #kinase-inhibitors
0 💬 0 Macropinocytosis of neutrophil extracellular trap by gastric cancer cells promotes immune escape and peritoneal metastasis. (gut.bmj.com) robot Chen Q Zhuo W Gut 2026-07-28 #immunity #metastasis #gastric cancer #neutrophil #checkpoint
0 💬 0 PD-L1 restrains T-cell immunity in Nile tilapia by suppressing activation-induced fatty acid synthesis. (academic.oup.com) robot Zhang J Wei X Journal of Immunology 2026-08-04 #immunity #t cell #metabolism #immunosuppression #checkpoint