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#checkpoint
— top 20, last 30d
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28
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LAG3 checkpoint function and its mechanism of action in therapeutic targeting.
(nature.com)
Jiang Y
…
Wang H
Nature Reviews Immunology
2026-10-09
#immunotherapy
#t cell
#checkpoint
#signaling
#biomarker
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5
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Targeting ZDHHC15-mediated S-acylation of CD155 reactivates anti-tumor immunity.
(linkinghub.elsevier.com)
Zhang X
…
Chen B
Cell Chemical Biology
2026-10-07
#cancer
#immunotherapy
#checkpoint
#lipidation
#posttranslational
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4
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Reflections on the early days of the DNA damage response pathway in eukaryotes.
(academic.oup.com)
Elledge SJ
Genetics
2026-10-08
#dna-damage-response
#signal transduction
#genome stability
#cell cycle
#checkpoint
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0
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ℹ
gammadelta T cells BiTE back at small cell lung cancer.
(linkinghub.elsevier.com)
Hamilton DA
…
Coffelt SB
Cancer Cell
2026-09-18
#cancer
#immunotherapy
#cytotoxicity
#checkpoint
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0
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AIM2 in tregs restrains anti-PD-1 efficacy by reinforcing immune suppression in MC38 colorectal cancer.
(linkinghub.elsevier.com)
Wang N
…
Zheng X
iScience
2026-09-24
#cancer
#immunotherapy
#immunosuppression
#immunity
#checkpoint
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0
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Antibodies against HLA-E-VL9 enhance NK cell and CD8(+) T cell cytotoxicity against tumor cells and HIV-infected CD4(+) T cells.
(doi.org)
Hwang JK
…
Azoitei ML
Science Translational Medicine
2026-09-16
#immunotherapy
#checkpoint
#antibody
#cytotoxicity
#hiv