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1
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A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics.
(nature.com)
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Gordzevich R
…
Brown ED
Nature
2026-06-24
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#biosynthesis
#antibiotic
#synergy
#natural products
#amr
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0
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Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.
(academic.oup.com)
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Lee YJ
…
Peters DL
Nucleic Acids Research
2026-06-22
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#phage
#nucleobase
#biosynthesis
#modification
#immunity
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0
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Tuning reductase activity in monoterpene indole alkaloid biosynthesis.
(pnas.org)
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Carr SC
…
O'Connor SE
PNAS
2026-06-23
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#metabolism
#alkaloids
#biosynthesis
#enzyme
#stereochemistry
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0
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Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets.
(pnas.org)
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Wang Y
…
Wang X
PNAS
2026-06-24
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#chemical ecology
#alkaloids
#biosynthesis
#evolution
#pharmacology
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0
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Identification and characterization of pumicyclin A, a novel circular bacteriocin from Bacillus pumilus with a dispensable leader peptide.
(journals.asm.org)
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Liu F
…
Ross RP
mBio
2026-06-24
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#bacteriocins
#amr
#biosynthesis
#food safety
#peptide
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0
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Complex multicellularity is linked with expanded specialized metabolite production in microorganisms.
(nature.com)
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Salamzade RA
…
Currie CR
Nature Microbiology
2026-06-26
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#specialized-metabolism
#multicellularity
#biosynthesis
#secondary metabolites
#evolution
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0
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Prime editing for precise genome engineering and modulation of fungal metabolism.
(nature.com)
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Sun C
…
Gao X
Nature Biotechnology
2026-06-30
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#base-editing
#genome engineering
#fungal
#metabolomics
#biosynthesis
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0
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Museomics reveals uncultured symbionts with biosynthetic potential in nudibranchs.
(link.springer.com)
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Porcel Sanchis D
…
Dzunkova M
Microbiome
2026-06-30
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#metagenomics
#symbiosis
#microbiome
#biosynthesis
#uncultured
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0
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A molecular timescale for evolution of cobamide biosynthesis.
(pnas.org)
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Wang J
…
Ge Y
PNAS
2026-07-01
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#evolution
#biosynthesis
#phylogenetics
#metabolism
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0
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Global distribution of isoprenoid quinones across Bacteria.
(journals.asm.org)
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Chobert S-C
…
Abby SS
mSystems
2026-07-01
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#phylogenetics
#biosynthesis
#metabolism
#genomics
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0
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DeepAden: an explainable machine learning method for predicting the substrate specificity of nonribosomal peptide synthetases.
(academic.oup.com)
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Huang J
…
Qin Z
Nucleic Acids Research
2026-07-03
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#nonribosomal peptides
#machine learning
#biosynthesis
#substrate-specificity
#natural products
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0
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Identification and distribution of a downregulatory signaling alkyloxazole in Streptomyces.
(pnas.org)
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Madden M
…
Li J
PNAS
2026-07-06
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#signaling
#secondary metabolism
#biosynthesis
#antibiotic
#genome mining
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0
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Cephalotaxinone enzymes reveal a whole plant model for homoharringtonine biosynthesis.
(nature.com)
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Dho Y
…
Sattely ES
Nature Chemical Biology
2026-07-06
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#biosynthesis
#alkaloid
#metabolomics
#transcriptomics
#enzyme
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0
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Identification of cellular intermediates unveils unique enzymes for flagellar glycan biosynthesis in Clostridioides difficile.
(pnas.org)
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Hensbergen PJ
…
Corver J
PNAS
2026-07-07
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#glycosylation
#biosynthesis
#virulence
#enzymology
#flagellar
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0
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Metabolic engineering of Synechocystis sp. PCC 6803 for olivetolic acid production.
(link.springer.com)
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Gao EB
…
Wu J
Microbial Cell Factories
2026-07-08
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#metabolic modeling
#cyanobacteria
#biosynthesis
#synthetic biology
#heterologous pathway
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0
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Rational selection of ketopantoate hydroxymethyltransferase with low product feedback inhibition based on binding free energy calculation analysis.
(journals.asm.org)
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Zheng K
…
Zheng Y-G
Applied and Environmental Microbiology
2026-07-10
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#metabolic modeling
#enzyme design
#computational modeling
#biosynthesis
#feedback inhibition
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