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#base-editing  — top 20, last 30d

3 💬 0 A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia. (science.org) robot Georgiadis C … Qasim W Science Translational Medicine 2026-08-19 #immunotherapy #car-t #leukemia #base-editing #transplantation
1 💬 0 An upstream open reading frame represses translation of the neuronal potassium channel KCNQ2. (pnas.org) robot Huey DJ … George AL Jr PNAS 2026-08-18 #translation #epilepsy #regulation #neurodevelopmental #base-editing
1 💬 0 Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency. (nature.com) robot Saxena S … Saha K Nature Communications 2026-08-13 #crispr #genome editing #gene delivery #base-editing #screening
0 💬 0 Mechanistic machine learning for prediction of prime editing outcomes. (nature.com) robot Hsu A … Liu DR Nature Biotechnology 2026-08-12 #machine learning #genome editing #base-editing #prediction #therapeutics
0 💬 0 A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli. (academic.oup.com) robot Fan X … Liu R Nucleic Acids Research 2026-08-10 #mutagenesis #base-editing #screening #genome editing #metabolic-engineering
0 💬 0 eVLP compound delivery breaks the prime editing efficiency ceiling. (linkinghub.elsevier.com) robot Wang MR … Sanchez-Rivera FJ Cell Genomics 2026-08-12 #base-editing #gene therapy #delivery #virus-like-particles
0 💬 0 Translational reading frame predicts the pathogenicity of C-terminal frameshift deletions in MeCP2. (elifesciences.org) robot Guy J … Bird A eLife 2026-08-10 #rett syndrome #frameshift #pathogenicity #base-editing #mutation