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12
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SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening.
(linkinghub.elsevier.com)
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Schmacke NA
…
Hornung V
Cell
2026-10-06
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#screening
#crispr
#imaging
#proteomics
#autophagy
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10
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Chaperone-mediated autophagy in physiological homeostasis, disease and ageing.
(nature.com)
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Kaushik S
…
Cuervo AM
Nature Reviews Molecular Cell Biology
2026-10-05
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#autophagy
#proteolysis
#aging
#neurodegeneration
#homeostasis
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4
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Disrupting BRD4-BD1-p62 engagement restores protective autophagy.
(linkinghub.elsevier.com)
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Zhang J
…
Ouyang L
Cell Chemical Biology
2026-10-08
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#autophagy
#fibrosis
#pulmonary
#inhibitor
#bromodomain
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3
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Nucleocytoplasmic shuttling of USP15 promotes pathological autophagy that disrupts neural stem cell homeostasis and neurodevelopment.
(jci.org)
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Burns KM
…
Yang G
Journal of Clinical Investigation
2026-10-06
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#neurodevelopment
#autophagy
#stemcells
#deubiquitination
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1
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Nitrate-responsive Sialin2 couples stress granule assembly and clearance to maintain neuronal homeostasis.
(linkinghub.elsevier.com)
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Li X
…
Wang S
Developmental Cell
2026-10-02
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#neurodegeneration
#stress-granules
#autophagy
#phase separation
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1
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A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation.
(nature.com)
|
Esposito A
…
Napolitano G
Nature
2026-09-30
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#autophagy
#lysosomal
#signaling
#lymphoma
#proteostasis
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1
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Oncogenic viral infection triggers LAMP2A SUMOylation and chaperone-mediated autophagy to promote tumorigenesis.
(nature.com)
|
Zhang Y
…
Cai Q
Nature Microbiology
2026-09-29
|
#autophagy
#herpesvirus
#oncogenic
#sumoylation
#tumorigenesis
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0
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|
Atg39-dependent nucleophagy and Atg40-dependent ER-phagy require the Apq12/Brr6/Brl1 complex.
(pnas.org)
|
Liu D
…
Novick P
PNAS
2026-09-30
|
#autophagy
#nucleophagy
#er-phagy
#membrane-remodeling
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0
|
|
ZBED6 deficiency drives pathological cardiac hypertrophy through MEOX1-ERK1/2-dependent autophagy dysfunction.
(journals.plos.org)
|
Zhang X
…
Wu J
PLOS Genetics
2026-10-01
|
#cardiomyopathy
#transcriptomics
#autophagy
#signaling
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0
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Kruppel-like factors regulate lipid homeostasis to modulate SKN-1/Nrf activity, oxidative stress resistance and longevity.
(academic.oup.com)
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Castillo-Quan JI
…
Moroz N
Genetics
2026-09-29
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#oxidative stress
#longevity
#lipid homeostasis
#transcription factor
#autophagy
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