Integrated screens reveal that guanine nucleotide depletion, which is irreversible via targeting IMPDH2, inhibits pancreatic cancer and potentiates KRAS inhibition. (gut.bmj.com)

Authors: Wu D … Shi S Journal: Gut Published: 2026-01-06 DOI: https://doi.org/10.1136/gutjnl-2025-336235