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1
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E2 displacement of CIP2A from TOPBP1 activates the DNA damage response during papillomavirus life cycles.
(linkinghub.elsevier.com)
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Prabhakar AT
…
Morgan IM
Cell Reports
2026-10-26
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#papillomavirus
#viral replication
#ddr
#cancer
#atm
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2
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The 9-1-1 complex protects ssDNA gaps in BRCA2-deficient cancer.
(linkinghub.elsevier.com)
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Grimsley HE
…
Powell SN
Molecular Cell
2026-10-26
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#cancer
#dna repair
#genomic instability
#homologous recombination
#brca2
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3
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Izalontamab brengitecan versus platinum-based chemotherapy in EGFR-mutated advanced non-squamous non-small-cell lung cancer after progression on third-generation EGFR tyrosine kinase inhibitors (PANKU-Lung01): a multicentre, randomised, open-label, phase 3 trial in China.
(linkinghub.elsevier.com)
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Hong S
…
Yang Y
The Lancet
2026-10-26
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#cancer
#clinical trial
#immunotherapy
#lung
#chemotherapy
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1
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UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling.
(linkinghub.elsevier.com)
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Wang J
…
Wei W
Cell Reports
2026-10-26
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#cancer
#signaling
#ubiquitination
#colorectal
#phosphorylation
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1
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Gut Clostridium aminophilum as a protective microbe in never-smoker lung cancer: insights from metagenomics and machine learning.
(journals.asm.org)
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Zhang J
…
Yu G
Microbiology Spectrum
2026-10-26
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#microbiome
#metagenomics
#cancer
#machine learning
#immunity
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