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0
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UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice.
(jci.org)
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Zhang B
…
Yang X
Journal of Clinical Investigation
2026-09-15
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#neurodegeneration
#mitophagy
#mitochondrial dysfunction
#neuroprotection
#drug discovery
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0
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Compound Z247611722 Exhibits Antifungal Activity by Inhibiting Serine Palmitoyltransferase.
(nature.com)
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Nysten J
…
Van Dijck P
Nature Communications
2026-09-15
|
#antifungal
#amr
#drug discovery
#sphingolipids
#candida
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0
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Rapamycin targetome mining identifies RBBP7 as a druggable epigenetic vulnerability in hepatocellular carcinoma.
(linkinghub.elsevier.com)
|
Gao Z
…
Zhang Y
Cell Chemical Biology
2026-09-15
|
#proteomics
#hepatocellular carcinoma
#epigenetics
#drug discovery
#histone
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0
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Discovery of the Nucleoside Analog FMAU as a Broad-Spectrum Anti-Orthopoxvirus Inhibitor In Vitro and In Vivo Using a Structure-guided Hit Expansion Strategy.
(tandfonline.com)
|
Zheng T
…
Fu L
Emerging Microbes & Infections
2026-09-15
|
#antiviral
#orthopoxvirus
#drug discovery
#nucleosides
#mpox
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