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6
|
|
KRAS is required for plexiform neurofibroma formation and represents a targetable vulnerability in established tumors.
(science.org)
|
Hu L
…
Ratner N
Science Advances
2026-09-04
|
#neurofibromatosis
#kras
#oncology
#immunotherapy
#pharmacology
|
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4
|
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Intratumoral injection of EpCAM BITE, IL-12, and GM-CSF mRNA-LNPs blocks the growth of local treated and distant untreated tumors.
(pnas.org)
|
Golubovskaya V
…
Wu L
PNAS
2026-09-04
|
#cancer
#immunotherapy
#rna
#cytokine
#t cell
|
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6
|
|
Synthetic long peptide and DNA personalized cancer vaccines induce robust neoantigen-specific T cell responses in pancreatic cancer.
(science.org)
|
Zhang Perkins F
…
Gillanders WE
Science Advances
2026-09-04
|
#immunotherapy
#pancreatic cancer
#neoantigens
#vaccination
#t cell
|
|
6
|
|
Messenger RNA delivery of a dual CD25/CD122 affinity-tuned IL-2 variant prolongs exposure and potentiates antitumor T cell immunity.
(science.org)
|
Vormehr M
…
Sahin U
Science Advances
2026-09-04
|
#cancer
#immunotherapy
#rna
#cytokine
#t cell
|
|
6
|
|
Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1-linked immunochemotherapy resistance in NSCLC via microbial metabolites.
(science.org)
|
Feng C
…
Zhang H
Science Advances
2026-09-04
|
#microbiome
#cancer
#immunotherapy
#dysbiosis
#metabolites
|
|
9
|
|
Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity.
(nature.com)
|
Gilioli D
…
Di Micco R
Nature Communications
2026-09-04
|
#leukemia
#immunotherapy
#senescence
#immunogenicity
#chemotherapy
|
|
6
|
|
Supramolecular immunomodulatory hydrogelator potentiates CAR-T therapy with long-lasting endogenous immunity toward solid tumor eradication.
(science.org)
|
Jiang C
…
Wang F
Science Advances
2026-09-04
|
#immunotherapy
#car-t
#immunosuppression
#tumor
#drug delivery
|