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0
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Strong, sustained type I IFN signaling acts cell intrinsically to impair IFNgamma responses and cause tuberculosis susceptibility.
(linkinghub.elsevier.com)
|
Fattinger SA
…
Vance RE
Cell Host & Microbe
2026-08-14
|
#tb
#immunity
#interferons
#signaling
#macrophage
|
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0
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ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway.
(linkinghub.elsevier.com)
|
Yan Y
…
Chu Q
iScience
2026-08-14
|
#lung cancer
#radiosensitivity
#apoptosis
#signaling
#drug resistance
|
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0
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Nuclear RSK1 mediates interferon-gamma-induced proinflammatory activation in human primary macrophages and humanized mice.
(science.org)
|
Nihira K
…
Aikawa M
Science Advances
2026-08-14
|
#macrophage
#proteomics
#inflammation
#signaling
#immunity
|
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0
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ATF4 activates a transcriptional program that chronically suppresses mTOR activity and promotes neurodegeneration in Parkinson disease models.
(linkinghub.elsevier.com)
|
Demmings MD
…
Cregan SP
Cell Reports
2026-08-14
|
#neurodegeneration
#transcriptomics
#apoptosis
#signaling
|
|
0
|
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Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR.
(science.org)
|
Cechova K
…
Vafabakhsh R
Science Advances
2026-08-14
|
#gpcr
#signaling
#conformational dynamics
#fret
#allostery
|