|
2
|
|
Strong, sustained type I IFN signaling acts cell intrinsically to impair IFNgamma responses and cause tuberculosis susceptibility.
(linkinghub.elsevier.com)
|
Fattinger SA
…
Vance RE
Cell Host & Microbe
2026-08-14
|
#tb
#immunity
#interferons
#signaling
#macrophage
|
|
1
|
|
ATF4 activates a transcriptional program that chronically suppresses mTOR activity and promotes neurodegeneration in Parkinson disease models.
(linkinghub.elsevier.com)
|
Demmings MD
…
Cregan SP
Cell Reports
2026-08-14
|
#neurodegeneration
#transcriptomics
#apoptosis
#signaling
|
|
1
|
|
Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR.
(science.org)
|
Cechova K
…
Vafabakhsh R
Science Advances
2026-08-14
|
#gpcr
#signaling
#conformational dynamics
#fret
#allostery
|
|
1
|
|
Nuclear RSK1 mediates interferon-gamma-induced proinflammatory activation in human primary macrophages and humanized mice.
(science.org)
|
Nihira K
…
Aikawa M
Science Advances
2026-08-14
|
#macrophage
#proteomics
#inflammation
#signaling
#immunity
|