#oncology — Wednesday, August 12, 2026 (3 items)
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Bronsted-basic small molecules activate GTP hydrolysis in KRAS-Q61 mutants.
(nature.com)
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Nature Chemical Biology 2026-08-12 | #oncology #kras #inhibitor #gtpase #drug discovery | |
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Belzutifan plus lenvatinib versus cabozantinib in patients with previously treated advanced renal cell carcinoma (LITESPARK-011): an open-label, randomised, controlled, phase 3 trial.
(linkinghub.elsevier.com)
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The Lancet 2026-08-12 | #renal cell carcinoma #clinical trial #immunotherapy #oncology #tyrosine-kinase-inhibitors | |
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Consensus on standardized later-line systemic therapy for hepatocellular carcinoma.
(linkinghub.elsevier.com)
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Drug Resistance Updates 2026-08-12 | #hepatocellular carcinoma #immunotherapy #targeted therapy #oncology #treatment-resistance |