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1
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Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice.
(science.org)
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Belgrad J
…
Khvorova A
Science Translational Medicine
2026-08-12
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#huntington's
#neurodegeneration
#rnai
#somatic-expansion
#therapeutics
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0
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Preclinical evaluation of nitrated alpha-synuclein-specific CAR-Treg therapy in Parkinson's disease.
(linkinghub.elsevier.com)
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Ugalde V
…
Pacheco R
Cell Reports Medicine
2026-08-12
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#immunotherapy
#neurodegeneration
#neuroinflammation
#car-t
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0
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Brain pro-resolving-to-pro-inflammatory lipids and cPLA(2) activation associations with late-life cognitive trajectories.
(linkinghub.elsevier.com)
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Yaskolka Meir A
…
Arvanitakis Z
EBioMedicine
2026-08-12
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#neurodegeneration
#lipidomics
#inflammation
#cognition
#transcriptomics
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0
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Mito-TEMPO improves survival rates in npc1-knockout zebrafish by reducing oxidative stress and enhancing mitophagy via Sod2.
(science.org)
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Zhao W
…
Cao H
Science Advances
2026-08-12
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#oxidative stress
#mitophagy
#lysosomal-storage-disorder
#neurodegeneration
#antioxidant
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0
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Long-term amyloid aggregation kinetic assay and rapid amyloid clustering enabled by programmable microdroplet water extraction.
(science.org)
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Cheong DY
…
Park I
Science Advances
2026-08-12
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#aggregation
#amyloid
#microfluidics
#kinetics
#neurodegeneration
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0
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Prediction of mild cognitive impairment progression using time-sensitive multimodal biomarkers.
(science.org)
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Gallego-Rudolf J
…
Villeneuve S
Science Advances
2026-08-12
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#neurodegeneration
#biomarker
#neuroimaging
#prediction
#neurophysiology
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