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0
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Selective loss of primary cilia and neurotrophic signaling in G51D alpha-synuclein mice highlights a common pathway to Parkinson's disease.
(pnas.org)
|
Lin YE
…
Pfeffer SR
PNAS
2026-08-10
|
#neurodegeneration
#cilia
#alpha-synuclein
#signaling
|
|
1
|
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The structural basis for LRRK2's activation and autoinhibition.
(linkinghub.elsevier.com)
|
Villagran Suarez A
…
Leschziner AE
Cell
2026-08-10
|
#neurodegeneration
#kinase
#cryo-em
#gtpase
#mutation
|
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0
|
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Zebrafish knockout models of atxn1a, atxn1b, and atxn1l reveal distinct and shared phenotypic and transcriptomic alterations.
(academic.oup.com)
|
Karim A
…
Orengo JP
Human Molecular Genetics
2026-08-10
|
#transcriptomics
#neurodegeneration
#crispr
#ataxia
#behavioral
|
|
0
|
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Chemical tools for inhibition and activity-based profiling of glucocerebrosidase in vitro and in vivo.
(linkinghub.elsevier.com)
|
Wang S
…
Phenix CP
Cell Chemical Biology
2026-08-10
|
#neurodegeneration
#inhibitor
#proteomics
|
|
0
|
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Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function.
(journals.plos.org)
|
Yanagi KS
…
Lehrbach N
PLOS Genetics
2026-08-10
|
#proteolysis
#ubiquitin
#protein degradation
#neurodegeneration
|