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0
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Cholesterol enhances lysosome-autophagosome fusion for better alpha-synuclein clearance in GBA L444P-mutated Parkinson disease.
(linkinghub.elsevier.com)
|
Chen M
…
Wang J
Cell Reports
2026-08-06
|
#neurodegeneration
#autophagy
#lysosome
#proteostasis
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0
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Distinct amyloid-beta filament fold in individuals with APP Flemish mutation.
(nature.com)
|
Khaki PSS
…
Hervas R
Nature Structural & Molecular Biology
2026-08-06
|
#neurodegeneration
#amyloid
#cryo-em
#structural biology
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0
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alpha-Synuclein blocks endoplasmic reticulum co-translational protein translocation early in Parkinson's disease.
(nature.com)
|
Lam CL
…
Tofaris GK
Nature Communications
2026-08-06
|
#proteomics
#neurodegeneration
#neurotoxicity
#protein misfolding
#transcriptomics
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0
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LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics.
(elifesciences.org)
|
Tombesi G
…
Greggio E
eLife
2026-08-06
|
#neurodegeneration
#synapse
#proteomics
#cytoskeleton
|