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#hepatocellular carcinoma
— Friday, July 31, 2026
(3 items)
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A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms.
(linkinghub.elsevier.com)
Wang S
…
Yu L
iScience
2026-07-31
#hepatocellular carcinoma
#apoptosis
#drug discovery
#anticancer
#hdac-inhibition
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Enhanced acetate uptake and metabolism in endothelial cells promote tumour angiogenesis and immunosuppression by increasing histone acetylation.
(gut.bmj.com)
Chen JY
…
Zhuang SM
Gut
2026-07-31
#immunosuppression
#angiogenesis
#metabolism
#epigenetics
#hepatocellular carcinoma
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Integrated single-cell multi-omics characterization reveals lipid-associated macrophage-mediated immunosuppression in neoadjuvant immunotherapy of hepatocellular carcinoma.
(nature.com)
Peng S
…
Li T
Nature Communications
2026-07-31
#immunotherapy
#single-cell
#hepatocellular carcinoma
#immunosuppression
#macrophage