|
0
|
|
Functional constraint, not evolutionary domain expansion, is a stronger correlate of pathogenic variant burden in human RNA-binding proteins.
(academic.oup.com)
|
Yasuda K
Human Molecular Genetics
2026-07-15
|
#pathogenicity
#protein-binding
#evolution
#constraint
#neurodegeneration
|
|
0
|
|
Multiscale brain development across the human lifespan.
(nature.com)
|
Ahmad S
…
Yap PT
Communications Biology
2026-07-15
|
#neuroimaging
#aging
#connectivity
#neurodegeneration
|
|
0
|
|
Cell-type signatures of Alzheimer's disease shared across population groups.
(nature.com)
|
Luquez T
…
Menon V
Nature
2026-07-15
|
#transcriptomics
#neurodegeneration
#single-cell
#epigenomics
#neuroinflammation
|
|
0
|
|
DDX3X syndrome mutations lock DDX3X-RNA conformational states to drive persistent pathological condensation and neuronal death.
(academic.oup.com)
|
Ghosh P
…
Kesavardhana S
Human Molecular Genetics
2026-07-15
|
#neurodegeneration
#stress-granules
#protein misfolding
#neurodevelopmental
#structural biology
|
|
0
|
|
Lysosomes and lysosomal dysfunction in ageing biology.
(nature.com)
|
Steinhauser ML
…
Tan JX
Nature Cell Biology
2026-07-15
|
#autophagy
#aging
#senescence
#inflammageing
#neurodegeneration
|
|
0
|
|
Functional segregation in Parkinson's disease.
(science.org)
|
Su D
…
Stoessl AJ
Science Advances
2026-07-15
|
#neurodegeneration
#dopamine
#basal ganglia
#neuroimaging
#motor control
|
|
0
|
|
Development of an RNA aptamer as a therapeutic agent for synucleinopathies.
(nature.com)
|
Murakami K
…
Bitan G
Nature Communications
2026-07-15
|
#aptamers
#synucleinopathy
#aggregation
#neurodegeneration
#therapeutics
|
|
0
|
|
Microglia integrated neural spheroids enable neuroinflammatory responses and correct network dysfunction induced by alpha-synuclein mutation.
(nature.com)
|
Zhang J
…
Lee EM
Communications Biology
2026-07-15
|
#neuroinflammation
#microglia
#organoid
#neurodegeneration
#ipsc
|
|
0
|
|
Immunotherapy with a short-lived anti-PD-L1 antibody in Alzheimer's disease: a phase 1b, randomized, double-blind trial.
(nature.com)
|
Croese T
…
Schwartz M
Nature Medicine
2026-07-15
|
#immunotherapy
#neuroinflammation
#neurodegeneration
#antibody
#clinical trial
|
|
0
|
|
The bone-cerebrovascular axis: effects of bone aging on neurovascular dysfunction and neurodegeneration.
(jci.org)
|
Wang J
…
Wan M
Journal of Clinical Investigation
2026-07-15
|
#aging
#neurodegeneration
#endocrine
#cerebrovascular
#osteoporosis
|
|
0
|
|
A small molecule reduces both parkinsonism and l-dopa-induced dyskinesia in animal models of Parkinson's disease.
(science.org)
|
Bordbar A
…
Famili I
Science Translational Medicine
2026-07-15
|
#neurodegeneration
#dyskinesia
#transcriptomics
#pharmacology
#therapeutics
|
|
0
|
|
The effect of physical activity on brain structure and cognitive function in the population-based cohort of LIFE-Adult Study.
(elifesciences.org)
|
Kalc P
…
Gaser C
eLife
2026-07-15
|
#neuroimaging
#cognition
#epidemiology
#aging
#neurodegeneration
|
|
0
|
|
Oligonucleotide-siRNA conjugate for SOD1 amyotrophic lateral sclerosis: a phase 1 trial.
(nature.com)
|
Chen W
…
Wang Y
Nature Medicine
2026-07-15
|
#rnai
#neurodegeneration
#cns-delivery
#clinical trial
|