#topoisomerase — Wednesday, May 20, 2026 (3 items)
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Bacterial type II topoisomerases cleave DNA in a species-specific manner.
(academic.oup.com)
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Nucleic Acids Research 2026-05-20 | #topoisomerase #amr #sequencing #dna | |
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Arginine methylation of human DNA topoisomerase I by PRMT5 facilitates DNA relaxation.
(academic.oup.com)
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Nucleic Acids Research 2026-05-20 | #methylation #cancer #dna damage #topoisomerase #chemotherapy | |
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Structural basis for asymmetric bis-intercalator targeting of DNA triplex junctions enabling dual inhibition of topoisomerase I and oncogene transcription.
(academic.oup.com)
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Nucleic Acids Research 2026-05-20 | #dna #cancer #topoisomerase #drug design #transcription |