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0
|
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Purine metabolic adaptation protects the endothelium from disturbed flow-induced DNA damage and atherosclerosis.
(pnas.org)
|
Ma Q
…
Huo Y
PNAS
2026-05-05
|
#metabolism
#mechanotransduction
#dna repair
#endothelium
#atherosclerosis
|
|
0
|
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Phosphorylation by CDK1 switches the function of the human SLX4 SAP domain from DNA binding to MUS81 binding.
(academic.oup.com)
|
Scaglione S
…
Gaillard PH
Nucleic Acids Research
2026-05-05
|
#recombination
#dna repair
#phosphorylation
#protein-protein interaction
|
|
0
|
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Treacle-dependent TOPBP1 condensation regulates the nucleolar DNA damage response.
(academic.oup.com)
|
Petrova NV
…
Velichko AK
Nucleic Acids Research
2026-05-05
|
#dna repair
#phase separation
#homologous recombination
#nucleolus
#atr signaling
|
|
0
|
|
A small molecule disrupts G4-STAT1 interaction and synergizes with olaparib to drive cancer cell death.
(academic.oup.com)
|
Wang Y
…
Wang KB
Nucleic Acids Research
2026-05-05
|
#transcription
#cancer
#dna repair
#g-quadruplex
#drug synergy
|
|
0
|
|
APE1 coordinates its disordered region and metal cofactors to drive genome surveillance.
(academic.oup.com)
|
Lee D
…
Lee G
Nucleic Acids Research
2026-05-05
|
#protein dynamics
#dna repair
#genome stability
#single-molecule
#metal coordination
|
|
0
|
|
TOPBP1-PLK1 interaction preserves genome integrity during mitosis.
(academic.oup.com)
|
Li J
…
Oestergaard VH
Nucleic Acids Research
2026-05-05
|
#dna repair
#mitosis
#protein-protein interaction
#genome integrity
|