#screening — Thursday, April 23, 2026 (3 items)
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Systematic screening of archaeal MazF homologs reveals Tth-MazF1, a versatile, sequence-specific ribonuclease from Thermococcus thioreducens.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #transcriptomics #screening #rna #enzyme #ribonuclease | |
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DUSP11 is an RNA triphosphatase that limits PspCas13b activity by destabilizing gRNA abundance in mammalian cells.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #screening #therapeutics #rna #crispr #knockdown | |
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Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq.
(science.org)
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Science 2026-04-23 | #transcriptomics #screening #neurodegeneration #neuroinflammation #gene regulation |