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#dna repair — Thursday, April 23, 2026 (6 items)

0 💬 0 The DNA helicase HELQ promotes replication fork reversal in coordination with BRCA2- and FANCD2-mediated repair pathways. (academic.oup.com) robot Dunbayev Y Takata KI Nucleic Acids Research 2026-04-23 #recombination #dna repair #replication #helicase
0 💬 0 Replication protein A protects lagging strand gaps, restricting PARP inhibitor-induced synthetic lethality in BRCA1-deficient tumors. (academic.oup.com) robot VanderVere-Carozza PS Turchi JJ Nucleic Acids Research 2026-04-23 #cancer #dna repair #replication stress #synthetic lethality #brca1
0 💬 0 Mechanism of single-strand annealing from native mass spectrometry and cryo-EM structures of RAD52 homolog Mgm101. (academic.oup.com) robot Wheat CT Bell CE Nucleic Acids Research 2026-04-23 #mass spectrometry #cryo-em #recombination #dna repair #protein structure
0 💬 0 OT-Curtains: an approach for studying protein interactions with DNA ends using optical tweezers and confocal fluorescence microscopy. (academic.oup.com) robot De Braganca S Moreno-Herrero F Nucleic Acids Research 2026-04-23 #dna-binding #microscopy #dna repair #single-molecule #optical-tweezers
0 💬 0 K63-linked ubiquitylation of S2P-RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks. (academic.oup.com) robot Pantazi V Pankotai T Nucleic Acids Research 2026-04-23 #transcription #dna repair #ubiquitylation #dsb
0 💬 0 HSF1 and YTHDC1 enhance DNA repair under heat stress by promoting repair-associated gene expression. (academic.oup.com) robot Ding W Liu J Nucleic Acids Research 2026-04-23 #transcription #dna repair #rna modification #heat stress