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0
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Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins.
(linkinghub.elsevier.com)
|
Gustafsen C
…
Glerup S
Cell Chemical Biology
2026-04-16
|
#therapeutics
#protein design
#proteolysis
#degradation
#lysosome
|
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0
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Assessing the suitability of deubiquitylases as substrates for targeted protein degradation.
(linkinghub.elsevier.com)
|
Tong J
…
Kodadek T
Cell Chemical Biology
2026-04-16
|
#ubiquitination
#protein degradation
#proteolysis
#protac
|
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0
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Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression.
(linkinghub.elsevier.com)
|
Liao C
…
Zhang Q
Cell Chemical Biology
2026-04-16
|
#cancer
#proteolysis
#kinase
#synthetic lethal
#protac
|
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0
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Receptor-ubiquitination-targeting antibody-drug conjugates for enhanced endocytosis and lysosomal delivery.
(linkinghub.elsevier.com)
|
Zhuang X
…
Pan L
Cell Chemical Biology
2026-04-16
|
#endocytosis
#cancer
#ubiquitination
#proteolysis
#adc
|
|
0
|
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IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes.
(linkinghub.elsevier.com)
|
Ma X
…
Vince JE
Cell Chemical Biology
2026-04-16
|
#cancer
#apoptosis
#ubiquitination
#proteolysis
#necroptosis
|
|
0
|
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Sorting out extracellular proteins: SORTACs harness sortilin for targeted protein degradation.
(linkinghub.elsevier.com)
|
Zhou C
…
Zhang X
Cell Chemical Biology
2026-04-16
|
#endocytosis
#immunotherapy
#proteolysis
#degradation
|
|
0
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Degrading TBK1 to disarm VHL-deficient renal cancer.
(linkinghub.elsevier.com)
|
Kwon H
…
Barbie DA
Cell Chemical Biology
2026-04-16
|
#cancer
#therapeutics
#proteolysis
|
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0
|
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Lysosome-targeting chimeras enable targeted protein degradation.
(linkinghub.elsevier.com)
|
Li B
…
Nie G
Cell Chemical Biology
2026-04-16
|
#endocytosis
#therapeutics
#proteolysis
#lysosome
|