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0
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ATM promotes PFKP nuclear translocation to balance glycolysis and homologous recombination repair.
(academic.oup.com)
|
Liu H
…
Wang J
Nucleic Acids Research
2026-04-13
|
#metabolism
#cancer
#dna repair
#phosphorylation
#radiotherapy
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0
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DNA-PKcs inhibitor AZD7648 reveals sgRNA cross-contaminants and enhanced sensitivity of genome engineering off-target activity in HSPCs.
(academic.oup.com)
|
White N
…
Turchiano G
Nucleic Acids Research
2026-04-13
|
#crispr
#dna repair
#genome editing
#off-target
#genotoxicity
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0
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Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replication fork protection in response to Top1-DNA crosslinks.
(academic.oup.com)
|
Courtes M
…
Pardo B
Nucleic Acids Research
2026-04-13
|
#dna repair
#replication
#genomic instability
#homologous recombination
#checkpoint
|
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0
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ACRC/GCNA is an essential protease that repairs DNA-protein crosslinks during vertebrate development.
(academic.oup.com)
|
Otten C
…
Popovic M
Nucleic Acids Research
2026-04-13
|
#crispr
#dna repair
#proteolysis
#genomic instability
|