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#dna repair — Thursday, March 19, 2026 (8 items)

0 💬 0 PE-STAR: prime editing with SOS-triggered and RecJ-augmented repair enables high-efficiency editing in Escherichia coli. (academic.oup.com) robot Duan X Liu R Nucleic Acids Research 2026-03-19 #synthetic biology #dna repair #genome engineering #bacterial genetics #base-editing
0 💬 0 TRF2-RAP1 inhibits homology-directed repair of telomeres by promoting BLM-mediated removal of telomere R-loops. (academic.oup.com) robot Liang F Chang S Nucleic Acids Research 2026-03-19 #recombination #dna repair #r-loops #telomere
0 💬 0 Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor. (academic.oup.com) robot Warren GM Shuman S Nucleic Acids Research 2026-03-19 #cryo-em #recombination #dna repair #nuclease #helicase
0 💬 0 Live-cell decoding of labile post-translational modifications in APE1 with a rationally engineered nano-catcher. (academic.oup.com) robot Zhang R Zhao M Nucleic Acids Research 2026-03-19 #proteomics #nanoparticles #cancer #dna repair #post-translational-modifications
0 💬 0 Endogenous promoter G-quadruplexes scaffold apurinic/apyrimidinic endonuclease (APE1) to drive gene expression. (academic.oup.com) robot Chen Y Bhakat KK Nucleic Acids Research 2026-03-19 #transcription #cancer #dna repair #g-quadruplex #ape1
0 💬 0 Poly(ADP-ribose) (PAR) exhibits ion-dependent structural properties distinct from RNA. (academic.oup.com) robot Baidya L Nguyen HT Nucleic Acids Research 2026-03-19 #modeling #dna repair #phase separation #simulation
0 💬 0 Indel pattern-guided repair mapping reveals genome-wide DNA repair networks in CRISPR/Cas9 editing. (academic.oup.com) robot Wan Y Huang L Nucleic Acids Research 2026-03-19 #crispr #dna repair #regulation #genome editing #clustering
0 💬 0 Enhancement of single-stranded template annealing activity by Rad52 during repair of CRISPR-induced dsDNA breaks. (academic.oup.com) robot Liu H Qi Q Nucleic Acids Research 2026-03-19 #recombination #crispr #dna repair #genome editing #homologous recombination