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0
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Sleep deprivation exhibits an age-dependent effect on infraslow global brain activity.
(pnas.org)
|
Yang Y
…
Liu X
PNAS
2026-03-17
|
#aging
#neurodegeneration
#sleep
#fmri
#glymphatic
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0
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Ubiquitin-specific peptidase-19 links TDP-43 aggregation to ER stress.
(pnas.org)
|
Yan Y
…
Kang DE
PNAS
2026-03-17
|
#aggregation
#neurodegeneration
#ubiquitination
#proteostasis
#er stress
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0
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Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer's disease.
(linkinghub.elsevier.com)
|
Luo S
…
Shen L
Cell Reports Medicine
2026-03-17
|
#proteomics
#neurodegeneration
#biomarker
#autophagy
#exosome
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0
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Identification of tofersen PD-response biomarkers in VALOR clinical trial CSF via multiplexed quantitative proteomics.
(linkinghub.elsevier.com)
|
Guise AJ
…
Graham DL
Cell Reports Medicine
2026-03-17
|
#proteomics
#pharmacodynamics
#neurodegeneration
#biomarker
|
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0
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A strategy of microglia replacement alleviates microgliopathy in a CSF1R I794T hotspot mutation mouse model of CSF1R-related disorder.
(linkinghub.elsevier.com)
|
Li X
…
Zheng H
Cell Reports Medicine
2026-03-17
|
#transcriptomics
#neurodegeneration
#microgliopathy
#leukoencephalopathy
#cell transplantation
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0
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Blood-brain barrier-penetrative lipid nanoparticles enable systemic delivery of TRIM11 mRNA to disaggregate Tau in Alzheimer's disease models.
(linkinghub.elsevier.com)
|
Zou Y
…
Shi B
Cell Reports Medicine
2026-03-17
|
#nanoparticles
#rna
#neurodegeneration
#neuroinflammation
#blood-brain barrier
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0
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Reversibility and beta-sheet formation are decoupled in tau condensate aging.
(pnas.org)
|
Fischer CM
…
Knowles TPJ
PNAS
2026-03-17
|
#aggregation
#neurodegeneration
#condensates
#proteostasis
#tau
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