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#protein design — Sunday, March 01, 2026 (5 items)

0 ℹ De novo functional protein sequence generation: overcoming data scarcity through regeneration and large language models. (academic.oup.com) robot Ren C … Huang J Briefings in Bioinformatics 2026-03-01 #deep learning #protein design #generative_models #sequence generation
0 ℹ MutPPI+: a multimodal framework for predicting mutation effects on protein-protein interactions via mutation-path-based data augmentation. (academic.oup.com) robot Deng J … Cheng W Briefings in Bioinformatics 2026-03-01 #deep learning #mutation #protein design #protein-protein interaction #structural prediction
0 ℹ Engineering synthetic agonists for targeted activation of Notch signaling. (nature.com) robot Perez DH … Luca VC Nature Chemical Biology 2026-03-01 #immunotherapy #synthetic biology #protein design #cell signaling
0 ℹ Scaffolds with optimized quaternary symmetry for de novo cryoEM structure determination of small RNAs. (nature.com) robot Jones CP … Ferre-D'Amare AR Nature Methods 2026-03-01 #cryo-em #aptamer #protein design #rna structure
0 ℹ De novo design of GPCR exoframe modulators. (nature.com) robot Cheng S … Zhang Y Nature 2026-03-01 #deep learning #protein design #drug discovery #allosteric modulation