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0
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Mapping the phenotypic landscape of a transcriptional repressor using deep mutational scanning and growth-based quantitative sequencing.
(academic.oup.com)
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Jansen Z
…
Thyer R
Nucleic Acids Research
2026-02-24
|
#transcription
#sequencing
#mutagenesis
#protein design
#phenotyping
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0
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Bacillus subtilis ParB C-terminal lysine residues are essential for dimerization and in vivo function, indicating their roles in DNA sliding.
(academic.oup.com)
|
Aleshintsev A
…
Kim H
Nucleic Acids Research
2026-02-24
|
#modeling
#mutagenesis
#biophysics
#protein-dna
#segregation
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0
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Highly mutagenic continuous evolution in E. coli using a Phi29-based orthogonal replication system.
(nature.com)
|
Rehm FBH
…
Chin JW
Nature Biotechnology
2026-02-24
|
#amr
#synthetic biology
#mutagenesis
#directed evolution
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0
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DNA secondary structures in BCL2 and MYC elicit activation-induced cytidine deaminase binding and activity.
(academic.oup.com)
|
McCrury M
…
Kendrick S
Nucleic Acids Research
2026-02-24
|
#immunity
#cancer
#mutagenesis
#deaminase
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0
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Selective control of ligand binding through a distal mutation that alters the protein native ensemble.
(pnas.org)
|
Dani R
…
Naganathan AN
PNAS
2026-02-24
|
#mutagenesis
#nmr
#folding
#conformational dynamics
#ligand-binding
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