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A comprehensive functional atlas of ALK kinase domain variants reveals resistance landscape to ALK inhibitors.
(link.springer.com)
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Genome Biology 2026-02-03 | #amr #cancer #mutagenesis #kinase #variant | |
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Structural basis for pseudokinase-mediated regulation of GCN2 in the integrated stress response.
(pnas.org)
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PNAS 2026-02-03 | #translation #signaling #stress response #protein structure #kinase |