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#neurodegeneration — Tuesday, January 27, 2026 (6 items)

0 💬 0 GFP-free live neuron quantitative imaging reveals compartmentalization and growth dynamics of polyQ aggregates. (pnas.org) robot Bi X Wei L PNAS 2026-01-27 #imaging #aggregation #microscopy #neurodegeneration
0 💬 0 Slippage reconfiguration of trinucleotide repeat hairpins impedes resolution by human replication protein A. (pnas.org) robot Kuang YC Lee IR PNAS 2026-01-27 #neurodegeneration #single-molecule #protein-dna #trinucleotide repeats #hairpin
0 💬 0 Nuclear MBL-1 modulates mitochondrial morphology through carnitine palmitoyltransferase in Caenorhabditis elegans with toxic trinucleotide repeats. (pnas.org) robot Teixeira J Garcia SMDA PNAS 2026-01-27 #metabolism #mitochondrial #neurodegeneration #rna binding #trinucleotide repeats
0 💬 0 Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. (elifesciences.org) robot Ozkan A Macklis JD eLife 2026-01-27 #transcription #neurodegeneration #differentiation #regeneration #neurogenesis
0 💬 0 Sleep loss induces cholesterol-associated myelin dysfunction. (pnas.org) robot Simayi R Bellesi M PNAS 2026-01-27 #metabolism #transcriptomics #neurodegeneration #myelin #sleep
0 💬 0 Caspase-3 cleaves and activates the NADase SARM1 to promote apoptosis, linking two cell death mechanisms. (pnas.org) robot Shi J Tessier-Lavigne M PNAS 2026-01-27 #metabolism #neurodegeneration #apoptosis #proteolysis