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0
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Engineered probiotics platform for oral delivery of antibody as a high-compliance alternative for immune-mediated inflammatory diseases.
(linkinghub.elsevier.com)
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Liu J
…
Wang Z
Cell Reports Medicine
2026-01-20
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#inflammation
#immunotherapy
#synthetic biology
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0
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c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors.
(linkinghub.elsevier.com)
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Balke-Want H
…
Feldman SA
Cell Reports Medicine
2026-01-20
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#cancer
#immunotherapy
#crispr
#car-t
#cytotoxicity
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0
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CAR-T triggers TAM reeducation and adaptive anti-tumor response via TREM2 deficiency or CD40 agonist.
(linkinghub.elsevier.com)
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Liu T
…
Tan J
Cell Reports Medicine
2026-01-20
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#metabolism
#cancer
#immunotherapy
#car-t
#macrophage
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0
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Targeting senescent EGR1(+) B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma.
(linkinghub.elsevier.com)
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Zhou P
…
Gu J
Cell Reports Medicine
2026-01-20
|
#immunity
#cancer
#inflammation
#immunotherapy
#senescence
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0
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.
(linkinghub.elsevier.com)
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Watterson A
…
Coelho MA
Cell Reports Medicine
2026-01-20
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#immunity
#cancer
#screening
#immunotherapy
#crispr
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0
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A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.
(linkinghub.elsevier.com)
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Psarrakis C
…
Giamarellos-Bourboulis EJ
Cell Reports Medicine
2026-01-20
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#microbiome
#infection
#dysbiosis
#immunotherapy
#prognosis
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0
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Targeting severe acidity for tumor-activatable Interleukin-2 therapy.
(linkinghub.elsevier.com)
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Feng Q
…
Gao J
Cell Reports Medicine
2026-01-20
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#nanoparticles
#cancer
#immunotherapy
#cytokine
#prodrug
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0
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An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery.
(linkinghub.elsevier.com)
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Gu C
…
Lu D
Cell Reports Medicine
2026-01-20
|
#cancer
#immunotherapy
#cytokine
#checkpoint
#exhaustion
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0
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Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer.
(linkinghub.elsevier.com)
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Newsome RC
…
Jobin C
Cell Reports Medicine
2026-01-20
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#microbiome
#metabolism
#immunity
#cancer
#immunotherapy
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0
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Engineered Akkermansia muciniphila vesicles for targeted pyroptosis and trained immunity to enhance immunotherapy in hepatocellular carcinoma.
(linkinghub.elsevier.com)
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Huang L
…
Wang F
Cell Reports Medicine
2026-01-20
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#nanoparticles
#immunity
#cancer
#immunotherapy
#pyroptosis
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0
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DF6215, an alpha-optimized IL-2-Fc fusion, expands immune effectors and drives robust preclinical anti-tumor activity.
(linkinghub.elsevier.com)
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Stockmann AP
…
Cheung AF
Cell Reports Medicine
2026-01-20
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#immunity
#cancer
#immunotherapy
#cytokine
#protein design
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0
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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer.
(linkinghub.elsevier.com)
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Zhan W
…
Deng Y
Cell Reports Medicine
2026-01-20
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#virulence
#immunity
#cancer
#immunotherapy
#proteolysis
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0
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5-HT reuptake blockade induces pyroptosis in BRAF(V600E)-mutated melanomas via remodeling histone serotonylation.
(linkinghub.elsevier.com)
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Li A
…
Lu X
Cell Reports Medicine
2026-01-20
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#amr
#epigenetics
#immunotherapy
#melanoma
#pyroptosis
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