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c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors.
(linkinghub.elsevier.com)
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Cell Reports Medicine 2026-01-20 | #cancer #immunotherapy #crispr #car-t #cytotoxicity | |
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CAR-T triggers TAM reeducation and adaptive anti-tumor response via TREM2 deficiency or CD40 agonist.
(linkinghub.elsevier.com)
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Cell Reports Medicine 2026-01-20 | #metabolism #cancer #immunotherapy #car-t #macrophage |